TY - JOUR T1 - Ambulatory treatment of low-risk pulmonary embolism in fragile patients: a subgroup analysis of the multinational Home Treatment of Pulmonary Embolism (HoT-PE) Trial JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.00663-2020 VL - 56 IS - 4 SP - 2000663 AU - Lukas Hobohm AU - Toni Anušić AU - Stavros V. Konstantinides AU - Stefano Barco A2 - , Y1 - 2020/10/01 UR - http://erj.ersjournals.com/content/56/4/2000663.abstract N2 - Pulmonary embolism is the third most frequent acute cardiovascular disease with an annual incidence of approximately 100 cases per 100 000 population and an annual mortality of ≥7 deaths per 100 000 population in the European region [1, 2]. Initial management is adjusted to the risk of in-hospital death or early complications, which depend both on the severity of pulmonary embolism and the presence of comorbidities [3].Early discharge and home treatment of acute pulmonary embolism in fragile patients appears to be feasible and acceptably safe. Caution is warranted due to the higher risk of major bleeding among fragile patients. https://bit.ly/2YtStiU ER -