TY - JOUR T1 - Building the house of CARDS by phenotyping on the fly JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.02429-2020 VL - 56 IS - 2 SP - 2002429 AU - Rajkumar Rajendram Y1 - 2020/08/01 UR - http://erj.ersjournals.com/content/56/2/2002429.abstract N2 - Some patients with coronavirus disease 2019 (COVID-19), fulfilling the Berlin criteria for acute respiratory distress syndrome (ARDS), do not respond well to the current treatment paradigm [1]. The perspective by Rello et al. [2] on phenotypes of COVID-19, and the editorial by Bos et al. [3], are therefore of great interest. The “responsible” phenotyping of COVID-19 ARDS (CARDS) recommended by Bos et al. [3] may be expedited by re-evaluating the existing literature on refractory hypoxia.Using clinical, pathophysiological and immunological phenotyping of ARDS to refine management of COVID-19 is urgently required to improve outcomes from refractory hypoxia https://bit.ly/2VvZe1p ER -