TY - JOUR T1 - The contribution of <em>Aspergillus fumigatus</em> to COPD exacerbations: a “sensitive” topic JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.02223-2020 VL - 56 IS - 2 SP - 2002223 AU - David Connell AU - Anand Shah Y1 - 2020/08/01 UR - http://erj.ersjournals.com/content/56/2/2002223.abstract N2 - Aspergillus fumigatus is a ubiquitous mould that can cause a spectrum of clinical disease ranging from invasive aspergillosis to allergic sensitisation depending on the host immune response [1]. The role of fungi and, in particular, A. fumigatus in driving COPD progression has been debated for many years. Susceptibility to invasive aspergillosis in COPD patients has been long reported and is now established as a significant risk factor [2]. The importance of fungi in COPD pathophysiology has curiously been raised for many years in the development of equine COPD which has been shown to be related to hypersensitivity to fungi (including A. fumigatus) in poor quality hay and straw bedding [3].Fungal sensitisation appears to play an important role in COPD disease progression https://bit.ly/30NcEcL ER -