TY - JOUR T1 - Added value of chest CT in suspected COVID-19: an analysis of 239 patients JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.01377-2020 SP - 2001377 AU - Daniël A. Korevaar AU - Ruud S. Kootte AU - Loek P. Smits AU - Joost G. van den Aardweg AU - Peter I. Bonta AU - Janke Schinkel AU - René M. Vigeveno AU - Inge A.H. van den Berk AU - Maeke J. Scheerder AU - Bregtje A. Lemkes AU - Abraham Goorhuis AU - Ludo F.M. Beenen AU - Jouke T. Annema A2 - , Y1 - 2020/01/01 UR - http://erj.ersjournals.com/content/early/2020/06/25/13993003.01377-2020.abstract N2 - Since the outbreak of the COVID-19 (coronavirus disease 2019) pandemic, clinicians have been struggling with the optimal diagnostic approach of suspected patients. RT-PCR (real-time reverse transcriptase-polymerase chain reaction) testing of respiratory samples is generally being considered as the reference standard for establishing SARS-CoV-2 infection [1]. However, RT-PCR results take hours to become available and, although highly specific, sensitivity is moderate [2–4]. This could result in delayed and suboptimal clinical decision making.“In a high-prevalence emergency department setting, chest CT showed a high probability of COVID-19 in 30% of patients with a negative or indeterminate initial RT-PCR result”Collaborators in the “Amsterdam UMC location AMC COVID-19 group” are: Josje Altenburg, Godelieve J. de Bree, Laurence M. Crombag, Marc R.W. Engelbrecht, Suzanne E. Geerlings, Tom van Gool, Martin P. Grobusch, Vanessa C. Harris, Thecla A.M. Hekker, Robert Hemke, Sabine M. Hermans, Jorrit J. Hofstra, Joppe W. Hovius, René E. Jonkers, Saskia Kolkman, Marnix P.M. Kop, Christof J. Majoor, Jeannine F. Nellen, Ikrame Oulad Abdennabi, Robrecht N. Planken, Tom van der Poll, Jan M. Prins, Adrienne van Randen, Peter Reiss, Charlotte A. van Ruitenbeek, Laura J. Schijf, Frank F. Smithuis, Veroniek Spoorenberg, Reindert P. van Steenwijk, Cornelis Stijnis, Femke Struik, Jeroen A.W. Tielbeek, Marc van der Valk, Anton Vonk Noordegraaf, Michèle van Vugt, Els J.M. Weersink, W. Joost Wiersinga, and Rens Zonneveld, all affiliated to the Amsterdam University Medical Centres, University of Amsterdam, the Netherlands. ER -