TY - JOUR T1 - Will children reveal their secret? The coronavirus dilemma JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.00749-2020 VL - 55 IS - 4 SP - 2000749 AU - Luca Cristiani AU - Enrica Mancino AU - Luigi Matera AU - Raffaella Nenna AU - Alessandra Pierangeli AU - Carolina Scagnolari AU - Fabio Midulla Y1 - 2020/04/01 UR - http://erj.ersjournals.com/content/55/4/2000749.abstract N2 - On 11 March, 2020, a novel human coronavirus, named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) became pandemic [1]. By 24 March, 372 757 SARS-CoV-2 confirmed cases and 16 231 related deaths have been reported worldwide [2]. In Italy, 62 844 cases and 5542 deaths have been reported, mostly in northern regions. Detailed data are updated by the Italian National Institute of Health [3].Epidemiological evidence shows that SARS-CoV-2 infection in children is less frequent and severe than adults. Age-related ACE2 receptor expression, lymphocyte count and trained immunity might be the keystone to reveal children's secret. https://bit.ly/2QWpWxK ER -