TY - JOUR T1 - Physiological predictors of exertional oxygen desaturation in patients with fibrotic interstitial lung disease JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.01681-2019 VL - 55 IS - 2 SP - 1901681 AU - Veronica Alfieri AU - Ernesto Crisafulli AU - Dina Visca AU - Wing Ho Chong AU - Carmel Stock AU - Letizia Mori AU - Angelo de Lauretis AU - Vicky Tsipouri AU - Felix Chua AU - Vasilis Kouranos AU - Maria Kokosi AU - Charlotte Hogben AU - Philip L. Molyneaux AU - Peter M. George AU - Toby M. Maher AU - Alfredo A. Chetta AU - Piersante Sestini AU - Athol U. Wells AU - Elisabetta A Renzoni Y1 - 2020/02/01 UR - http://erj.ersjournals.com/content/55/2/1901681.abstract N2 - In patients with fibrotic interstitial lung disease (ILD), hypoxaemia on exertion is frequent, and contributes to exercise intolerance, exertional dyspnoea and reduced quality of life [1–3]. Clinically significant exertional hypoxaemia is typically defined as a drop in transcutaneous arterial oxygen saturation (SpO2) to ≤88% on a 6-min walk test (6MWT) [4], and is associated with reduced survival in ILD patients [5].In patients with interstitial lung disease, exertional hypoxaemia has quality of life and prognostic implications. A simple “DeOX” score predictive of exertional oxygen desaturation (SpO2 ≤88% on 6MWT) is proposed, using SpO2 at rest and DLCO. http://bit.ly/36ytigE ER -