%0 Journal Article %A Sabina Guler %A Luc Bovet %A Patrick Brun %T Inpatient pulmonary rehabilitation improves functional independence in patients with interstitial lung disease %D 2019 %R 10.1183/13993003.congress-2019.PA3413 %J European Respiratory Journal %P PA3413 %V 54 %N suppl 63 %X Background: Regaining independence in functions of daily living is a key goal of inpatient pulmonary rehabilitation (IPR).Objective: To quantify the effect of IPR on functional independence in patients with fibrotic interstitial lung disease (ILD), and to determine the importance of change in 6-minute-walk distance (6MWD) for functional independence.Methods: Consecutive patients with fibrotic ILD who attended a 3-week IPR program were included. The functional independence measure (FIM) and 6MWD and were collected at IPR admission and discharge.Results: We included 33 men and 17 women with fibrotic ILD (17 with idiopathic pulmonary fibrosis), with a mean (standard deviation, SD) age of 72 (14) years, FVC of 65 (19) %-predicted, and DLCO of 37 (13) %-predicted. At baseline mean (SD) 6MWD was 215 (111) meters/43 (20) %-predicted, with significant increase after IPR (mean difference [95%-confidence interval, CI] 45 [30-61] meters, p<0.001). Total FIM increased after IPR (mean difference [95%CI] 9.24 [6.4-12.1], p<0.001). On unadjusted analysis gain in 6MWD correlated significantly with gain in FIM in men (r=0.52, p=0.003), but not in women (r=0.01, p=0.99). The chance of a substantial gain in FIM (highest quartile) was significantly higher in patients who increased 6MWD during IPR (OR 1.08 per %6MWD-pred., 95%CI 1.01-1.19, p=0.04), including with adjustment for age and sex.Conclusion: IPR effectively increases functional independence in patients with fibrotic ILD. The increase of 6MWD during IPR correlates significantly with gain in FIM, suggesting that the improvement of physical performance translates into more independence in daily life.FootnotesCite this article as: European Respiratory Journal 2019; 54: Suppl. 63, PA3413.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). %U