RT Journal Article
SR Electronic
T1 The prevalence of restrictive lung function in a general population obtained by spirometry and bodyplethysmography-Data from the LEAD study
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP PA358
DO 10.1183/13993003.congress-2019.PA358
VO 54
IS suppl 63
A1 Robab Breyer-Kohansal
A1 Marie-Kathrin Breyer
A1 Otto Burghuber
A1 Andreas Horner
A1 Bernd Lamprecht
A1 Alina Ofenheimer
A1 Andrea Schrott
A1 Sylvia Hartl
YR 2019
UL http://erj.ersjournals.com/content/54/suppl_63/PA358.abstract
AB Published prevalence data on restrictive lung function (rLF) in the general population vary widely from 5-20% and are obtained by spirometry only. Therefore, the aim of our study was to determine the prevalence and severity of rLF in a general population according to both spirometric and bodyplethsymographic excepted equations.Data was obtained from the Austrian LEAD Study, a longitudinal, observational, population-based cohort study. In total 9998 participants (46.6% male) were included in this analysis. rLF was defined spirometrically by FEV1/FVC>LLN and FVC<LLN and bodyplethysmographically by TLC<LLN. Severity of rLF was defined as mild (>60%pred), moderate (40-60%pred) and severe (<40%pred).Overall, the prevalence of rLF by spirometric criteria is 3.4% (N=337) and by bodyplethysmographic criteria 0.9% (N=85; p<0.001). rLF is more prevalent in male vs. female (1.6 vs 0.2; p<0.001; Table1) and independent of age, although no rLF was found in age <18years. Nearly all rLF were mild, independently from the parameter used (FVC% or TLC%), which both are highly correlated (R=0.6, p<0.001).The prevalence of rLF in our general population is significantly less than previously reported; especially when bodyplethysmographic criteria are applied. Therefore, existing prevalence data on rLF may be interpreted with caution and should be validated by bodyplethysmography in the future.FootnotesCite this article as: European Respiratory Journal 2019; 54: Suppl. 63, PA358.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).