PT - JOURNAL ARTICLE AU - Abdelbassat Ketfi AU - Merzak Gharnaout AU - Leila Triki AU - Helmi Ben Saad TI - The impact of parity on lung function data (LFD) of Algerian healthy females aged > 40 Yrs: a comparative study AID - 10.1183/13993003.congress-2019.PA801 DP - 2019 Sep 28 TA - European Respiratory Journal PG - PA801 VI - 54 IP - suppl 63 4099 - http://erj.ersjournals.com/content/54/suppl_63/PA801.short 4100 - http://erj.ersjournals.com/content/54/suppl_63/PA801.full SO - Eur Respir J2019 Sep 28; 54 AB - Introduction: Studies evaluating the impact of parity on LFD of healthy females presented controversial conclusions.Aims: To compare the LFD of 2 groups of healthy females divided according to their parities, and to determine the relationship between parity and LFD.Methods: A medical questionnaire was administered and anthropometric data were determined. Parity was introduced as numeric and as dichotomous [G1 ≤ 6; G2 > 6]. LFD (plethysmography data and specific airway resistance (SRaw)] were collected. Correlation-coefficient (r) and Student’s t-test were used, respectively, to evaluate the relationships between parity and LFD (absolute values) and to compare the two groups’ mean±SD quantitative data.Results: G1 (n=34) and G2 (n=32) were age- and height-matched (58±9 vs. 62±8 Yrs; and 1.55±0.06 vs. 1.56±0.05 m, respectively). Compared to GI, G2 had a lower body mass index (30.0±3.60 vs. 27.6±3.4 kg/m2) and a higher parity (4±1 vs. 10±2). G1 and G2 had similar values of forced expiratory volume in 1 s (FEV1), forced or slow vital capacity (FVC, SVC), maximal mid-expiratory flow, forced expiratory flow at x% of FVC, peak expiratory flow, expiratory and inspiratory reserve volumes, inspiratory capacity, sRaw, FEV1/FVC, FEV1/SVC, and residual volume/total lung capacity ratio (RV/TLC). Compared to G1, G2 had significantly higher thoracic gas volume (TGV: 2.68±0.43 vs. 3.00±0.47 L), RV (1.80±0.29 vs. 2.04±0.33 L) and TLC (4.77±0.62 vs. 5.11±0.67 L). In the total sample, significant positive correlations were found between parity and TGV (r=0.31), RV (r=0.33), and TLC (r=0.25).Conclusion: Increasing parity induced a tendency towards lung hyperinflation.FootnotesCite this article as: European Respiratory Journal 2019; 54: Suppl. 63, PA801.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).