PT  - JOURNAL ARTICLE
AU  - Raja Dhar
AU  - Girija Nair
AU  - Ram Jana
AU  - Arti Shah
AU  - Alpa Dalal
AU  - Srinivas Rajagopala
AU  - Malay Sarkar
AU  - Jaymohan Unnithan
AU  - Arpan Shah
AU  - Srikanth Krishnamurthy
AU  - Praveen Shahi
AU  - Shahid Patel
AU  - Vipin Chaudhary
AU  - Prasad Patil
AU  - Priyanka Karumalai
AU  - Palak Shah
AU  - Shobana Balasubramaniam
AU  - sruthi J
AU  - Nisha Kale
AU  - Sapna Madas
AU  - Sneha Limaye
AU  - Shrikant Pawar
AU  - Sundeep Salvi
TI  - Phenotyping Post TB Obstructive airways disease (TOPD) in India
AID  - 10.1183/13993003.congress-2019.PA734
DP  - 2019 Sep 28
TA  - European Respiratory Journal
PG  - PA734
VI  - 54
IP  - suppl 63
4099  - http://erj.ersjournals.com/content/54/suppl_63/PA734.short
4100  - http://erj.ersjournals.com/content/54/suppl_63/PA734.full
SO  - Eur Respir J2019 Sep 28; 54
AB  - Aims and Objectives: To study the characteristics, severity of airflow limitation and prescription pattern in TOPD patients in India.Introduction: There is a paucity of data reported from India on the TOPD phenotype and understanding of the disease process.Methods: A semi-structured questionnaire was prepared by Respiratory Research Network of India and was filled by the investigator at the study sites across India.Results: 103 patients were identified as having post TOPD 9 (8.7%) had mild disease, 39 (37.9%) had moderate, 37 (35.9%) severe and 18 (17.5%) were diagnosed as very severe TOPD. Significant negative correlation (r= -0.499, p value =0.021) was observed between duration of TOPD and patients with severe TOPD. The Pearson Chi square test showed a significance association (p value=0.033) between occurrence of post-TOPD and affected left middle zone. Reversibility was observed in 24 (23.3%) patients and fixed airflow obstruction was observed in 79 (76.7%) patients respectively. Prescription pattern showed that, LAMA alone was prescribed to 5 (5%), LABA and LAMA combination to 10 (10%), LABA and ICS combination to 20 (20%), LAMA and ICS to 5 (5%), LAMA, LABA and ICS combination to 60 (60%) cases. Mild disease was most commonly prescribed with LABA+ICS (66.66 %), moderate with LAMA+LABA+ICS (77%), severe with LABA+ICS (32.35%) and very severe cases with LAMA+LABA+ICS (83.3%). %). Hence the treatment regime was not in accordance with the GINA or GOLD guidelines.Conclusion: The current study emphasis on the importance of screening of post-TOPD. This study presented the association of post-TOPD on the lung function and the prescription pattern currently followed for the treatment of post-TOPD.FootnotesCite this article as: European Respiratory Journal 2019; 54: Suppl. 63, PA734.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).