@article {DharPA734, author = {Raja Dhar and Girija Nair and Ram Jana and Arti Shah and Alpa Dalal and Srinivas Rajagopala and Malay Sarkar and Jaymohan Unnithan and Arpan Shah and Srikanth Krishnamurthy and Praveen Shahi and Shahid Patel and Vipin Chaudhary and Prasad Patil and Priyanka Karumalai and Palak Shah and Shobana Balasubramaniam and sruthi J and Nisha Kale and Sapna Madas and Sneha Limaye and Shrikant Pawar and Sundeep Salvi}, title = {Phenotyping Post TB Obstructive airways disease (TOPD) in India}, volume = {54}, number = {suppl 63}, elocation-id = {PA734}, year = {2019}, doi = {10.1183/13993003.congress-2019.PA734}, publisher = {European Respiratory Society}, abstract = {Aims and Objectives: To study the characteristics, severity of airflow limitation and prescription pattern in TOPD patients in India.Introduction: There is a paucity of data reported from India on the TOPD phenotype and understanding of the disease process.Methods: A semi-structured questionnaire was prepared by Respiratory Research Network of India and was filled by the investigator at the study sites across India.Results: 103 patients were identified as having post TOPD 9 (8.7\%) had mild disease, 39 (37.9\%) had moderate, 37 (35.9\%) severe and 18 (17.5\%) were diagnosed as very severe TOPD. Significant negative correlation (r= -0.499, p value =0.021) was observed between duration of TOPD and patients with severe TOPD. The Pearson Chi square test showed a significance association (p value=0.033) between occurrence of post-TOPD and affected left middle zone. Reversibility was observed in 24 (23.3\%) patients and fixed airflow obstruction was observed in 79 (76.7\%) patients respectively. Prescription pattern showed that, LAMA alone was prescribed to 5 (5\%), LABA and LAMA combination to 10 (10\%), LABA and ICS combination to 20 (20\%), LAMA and ICS to 5 (5\%), LAMA, LABA and ICS combination to 60 (60\%) cases. Mild disease was most commonly prescribed with LABA+ICS (66.66 \%), moderate with LAMA+LABA+ICS (77\%), severe with LABA+ICS (32.35\%) and very severe cases with LAMA+LABA+ICS (83.3\%). \%). Hence the treatment regime was not in accordance with the GINA or GOLD guidelines.Conclusion: The current study emphasis on the importance of screening of post-TOPD. This study presented the association of post-TOPD on the lung function and the prescription pattern currently followed for the treatment of post-TOPD.FootnotesCite this article as: European Respiratory Journal 2019; 54: Suppl. 63, PA734.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).}, issn = {0903-1936}, URL = {https://erj.ersjournals.com/content/54/suppl_63/PA734}, eprint = {https://erj.ersjournals.com/content}, journal = {European Respiratory Journal} }