PT  - JOURNAL ARTICLE
AU  - Ankit Kumar Sinha
TI  - Body composition analysis in COPD patients admitted in ICU with acute exacerbation
AID  - 10.1183/13993003.congress-2019.PA3989
DP  - 2019 Sep 28
TA  - European Respiratory Journal
PG  - PA3989
VI  - 54
IP  - suppl 63
4099  - http://erj.ersjournals.com/content/54/suppl_63/PA3989.short
4100  - http://erj.ersjournals.com/content/54/suppl_63/PA3989.full
SO  - Eur Respir J2019 Sep 28; 54
AB  - Introduction: COPD is a systemic inflammatory condition. Inflammation and actions of pro-inflammatory mediators may extend beyond the lungs and play a part in COPD co-morbidities and causing multiple extra-pulmonary manifestations.Objective: To co-relate with Fat free mass and number of acute exacerbation of COPD.Methods: The prospective observational study included 64 patients and studied body mass composition by body impedance analyser on patients admitted with COPD and severe acute exacerbation in hospital and correlated Fat Free Mass(FFM), Fat Free Mass Index(FFMI), Muscle Mass(MM), Bone Mass, Body water along with BMI of patients with Spirometry, Muscle pressures and 6MWD(Six minute walk distance) results, which were subjected to statistical analysis.Results: Majority of patients were male(75%) with mean age of 67.44+/- 8.53 years. Average Body mass index(BMI) was 22.85+/-5.27kg/m2 with fat free mass(FFM) & fat free mass index(FFMI) were 43.26+/-8.3kg/m2 and 16.40+/-2.45 kg/m2 respectively. The muscle mass and bone mass were 40.97+/-7.86kg and 2.29+/- 0.45 kg respectively. There functional capacity markers showed FVC 73.18+/-19.59%, FEV1 51.31+/- 21.87% and 6MWD of 278.92+/-103.13 meter.Conclusion: COPD patients with acute exacerbation despite normal BMI had low FFM, low FFMI, muscle mass, bone mass, indicating high Fat mass, correlating with poor lung and respiratory muscles functions.FootnotesCite this article as: European Respiratory Journal 2019; 54: Suppl. 63, PA3989.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).