RT Journal Article
SR Electronic
T1 Validation of the IPF-specific version of St. George’s Respiratory Questionnaire in Danish
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP PA4687
DO 10.1183/13993003.congress-2019.PA4687
VO 54
IS suppl 63
A1 Thomas Skovhus Prior
A1 Nils Hoyer
A1 Saher Shaker
A1 Jesper Rømhild Davidsen
A1 Janelle Yorke
A1 Ole Hilberg
A1 Elisabeth Bendstrup
YR 2019
UL http://erj.ersjournals.com/content/54/suppl_63/PA4687.abstract
AB Introduction: Quality of life is impaired in patients with idiopathic pulmonary fibrosis (IPF) due to both physical and psychological deficits. The IPF-specific version of St. George’s Respiratory Questionnaire (SGRQ-I) is a validated measure of health-related quality of life. This study was conducted to validate the Danish version of SGRQ-I.Methods: At baseline, patients with IPF completed SGRQ-I, St. Georges Respiratory Questionnaire (SGRQ), University of California, San Diego Shortness of Breath Questionnaire (SOBQ) and Short Form-36 (SF-36), and lung function tests were performed. SGRQ-I and Global Rating of Change Scales were completed 14 days later. Internal consistency, concurrent validity, test-retest reliability and known groups validity were estimated.Results: The questionnaires were completed by 150 patients at baseline and by 144 patients after 14 days. Internal consistency was high in SGRQ-I (Cronbach’s α: 0.92). Good concurrent validity of SGRQ-I compared to SGRQ was demonstrated by high intraclass correlation coefficient (ICC 0.97) and Bland Altman plots. Also, SGRQ-I had moderate to strong correlations to SOBQ and SF-36 (r = 0.46-0.80) along with moderate to weak correlations to lung function and 6-minute walk test (r = 0.30-0.50). High ICC (0.92) and a Bland Altman plot indicated good test-retest reliability of the questionnaire. SGRQ-I was able to discriminate patients with different stages of disease.Conclusion: The Danish version of the SGRQ-I is valid and reliable as a measure of quality of life in patients with IPF and performs equally to the English version. Studies of responsiveness of SGRQ-I and factors associated with impaired quality of life are ongoing.FootnotesCite this article as: European Respiratory Journal 2019; 54: Suppl. 63, PA4687.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).