%0 Journal Article %A Rebeca Martins Natal %A Gonçalo Samouco %A Marcos Oliveira %A João Fernandes Costa %A Denisa Mendonça %A Luís Vaz Rodrigues %T Pneumococcal vaccination in chronic respiratory patients – a cohort study %D 2019 %R 10.1183/13993003.congress-2019.PA2886 %J European Respiratory Journal %P PA2886 %V 54 %N suppl 63 %X Introduction: Pneumococcal vaccination (PV) is generally recommended for chronic respiratory patients (CRP). Data on real life compliance is scarce and heterogeneous, but usually unveils an overall low adherence to PV1.Aims: To ascertain whether PV is beneficial in the occurrence and severity of respiratory infections (RI) in CRP.Methods: We conducted a prospective cohort study of CRP that attended our pulmonary outpatient clinic from October 2017 to February 2018 and had previously participated in our survey1. A 12-month follow up of this cohort was made to evaluate the presence of RI. From those infected, Fisher’s test was used to compare the percentage of vaccinated and unvaccinated patients in the outcomes of hospitalization, use of antibiotics (AB) and death.Results: From the total of 201 in the survey, 199 patients were included in this cohort. Mainly men (59.8%), 65.4 (SD=15.2) years, 8% current smokers and 37% former smokers, 82% with low educational status. Major diagnosis were asthma (31.7%) and COPD (29.1%). PV coverage increased 15.4% in a year, currently 57·8%. Globally, 34.2% (n=68) of this cohort had any kind of RI occurring more frequently in vaccinated (41.8% v (27.5%, p=0,042) patients. Comparing both groups we found that a similar use of AB (100% v 97.8%, p=1.00), but lesser hospitalizations (37.0% v 50.0%, p=0.307) and lesser deaths (4.3% v 18.2%, p=0.081) were reported in vaccinated as opposed to unvaccinated CRP.Conclusions: In this year follow up, PV had already a beneficial impact in decreasing the severity of RI in CRP.Reference:1. Martins RN, Vaz LR. Influenza and Pneumococcal Vaccination in Chronic Respiratory Patients-Are We in the Right Path?. Arch bronconeumol. 2019 JanFootnotesCite this article as: European Respiratory Journal 2019; 54: Suppl. 63, PA2886.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). %U