PT - JOURNAL ARTICLE AU - Leandro Azeredo AU - Leonardo Souza AU - Bruno Guimarães AU - Jocemir Lugon TI - Effect of inspirational muscle training in patients with obstructive sleep apnea AID - 10.1183/13993003.congress-2019.PA4179 DP - 2019 Sep 28 TA - European Respiratory Journal PG - PA4179 VI - 54 IP - suppl 63 4099 - http://erj.ersjournals.com/content/54/suppl_63/PA4179.short 4100 - http://erj.ersjournals.com/content/54/suppl_63/PA4179.full SO - Eur Respir J2019 Sep 28; 54 AB - Introduction: Obstructive sleep apnea syndrome (OSAS) is common and is associated with serious consequences of cardiovascular diseases and quality of life.Objective: This study aim to compare the intervention with an inspiratory muscle training (IMT) in relation a SHAM in patients with obstructive sleep apnea (OSA).Methods: Clinical, controlled and randomized trial. Subjects will be submitted to analyses before and after period of 3 months to: polysomnography, maximal inspiratory pressure (MIP) measurement, Pittsburgh scale questionnaires for sleep quality assessment, Epworth scale for daytime sleepiness assessment, Short Form-36 for health quality of life assessment and Berlim questionnaire for assess the risk of obstructive sleep apnea. Intervention group will perform IMT with an initial load of 40% of the MIP, increasing 10% each week until achieve 60% of MIP, performed daily with 30 inspiratory exercises, for 12 weeks on the POWERbreathe® medic (POWERbreathe, UK). Statistical significance was P<0.05.Results: With 53 subject selected (31 intervention group and 22 SHAM) there was a tendency to increase MIP (P<0.001), with improvement of apnea and hypopnea index (P=0.052), reduction of Epworth scale score (P=0.012) and higher sleep quality in Pittsburgh scale (P<0.001). Variables SF-36 and the Berlin scale did not present statistical significance between intervention group and sham group (P=1.00).Conclusion: Preliminaries data showed that IMT with POWERbreathe® medic can reduce daytime hypersonness signs, improve the quality of sleep impacting on apneia and hypopneia index of polysomnography and may become a new alternative treatment for patients with obstructive sleep apnea syndrome.FootnotesCite this article as: European Respiratory Journal 2019; 54: Suppl. 63, PA4179.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).