RT Journal Article SR Electronic T1 Exercise-induced airway symptoms from adolescence to early adulthood, a five-year follow-up JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP OA1938 DO 10.1183/13993003.congress-2019.OA1938 VO 54 IS suppl 63 A1 Henrik Johansson A1 Margareta Emtner A1 Christer Janson A1 Leif Nordang A1 Andrei Malinovschi YR 2019 UL http://erj.ersjournals.com/content/54/suppl_63/OA1938.abstract AB Introduction: Exercise-induced airway symptoms are common among adolescents. The development of such symptoms with age has not been studied.Aim: To investigate the course of exercise-induced airway symptoms with age from adolescence to early adulthood.Methods: At baseline, in 2011, all 12-13-year-old adolescents in Uppsala (n=3838) were sent a questionnaire on exercised-induced airway symptoms during the last year (throat tightness, hoarseness, inspiratory stridor, cough, chest tightness, wheeze, dyspnea). The response rate was 60%. At follow-up, in 2016, the questionnaire was sent, once again, to all responders at baseline (n=2309), now 17-18-year-old. In total, 1002 adolescents answered the questionnaire at both time-points.Results: The prevalence of one or more exercised-induced airway symptoms among the participating adolescents increased from 27.5% at baseline to 50% at follow-up (p<0.001). The most common symptoms were cough, dyspnea, and throat tightness or chest tightness. More females than males reported one or more airway symptoms, both at baseline (30.7 vs. 22.6%, p=0.004) and at follow-up (55.5 vs. 42.7%, p<0.001). Among participants with only one symptom at baseline, 48% reported total remission at follow-up. In participants with 2-3 symptoms, 34% reported remission and in those with ≥4 symptoms, only 16% reported total remission at follow-up. Over all males reported higher remission of all different symptoms, except for cough, compared to females.Conclusions: Self-reported exercise-induced airway symptoms increase with age and the prevalence is higher among females. Adolescents reporting several different airway symptoms are less likely to report remission five years later.FootnotesCite this article as: European Respiratory Journal 2019; 54: Suppl. 63, OA1938.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).