TY - JOUR T1 - The timed inspiratory effort index as a weaning predictor: analysis of intra and inter-observer reproducibility JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2019.PA1138 VL - 54 IS - suppl 63 SP - PA1138 AU - Leonardo Souza AU - Arthur Silva Neto AU - Leo Ribeiro AU - Jocemir Lugon Y1 - 2019/09/28 UR - http://erj.ersjournals.com/content/54/suppl_63/PA1138.abstract N2 - Objective: To evaluate the reproducibility of “timed inspiratory effort index" as a weaning predictor, by analyzing the intra and inter-observer of patients on weaning ventilation. Method: This prospective observational study, included patients judged able to start weaning. They were separated in intra and inter-observer groups. The exams were evaluate for weaning outcome by two observers independently, after an interval of 30 minutes for the new assessment. The endpoints will be to compare of the coefficient concordance of Kappa, variation of Bland-Altman and the performance of the TIE index through of area under the ROC curves Analysis. P values <0.05 were considered significant.Results: Were selected 113 patients (43 male, mean age 77 ± 14 years), 56 (49.6%) achieved successful wean and 33 (29%) had a fatal course. Tracheotomy was necessary in 63 (55.8%) patients, the mean duration of mechanical ventilation was 14.4 ± 6.7 days and APACHE II score was 18.9 ± 5.5. The PImáx and the TIE index to all measures did not show a statistically significant difference. When the measures were compared in the intra and inter-observational groups respectively showed by coefficient concordance of Kappa 0.79 (0.63-0.95) and 0.55 (0.32-0.77), variation of Bland-Altman 20.7±0.2 and 25.4±0.3. More relevant the areas under the ROC curves for all groups which were similar, Intra (0.96 ± 0.07 vs. 0.94 ± 0.07, P = 0.41) and Inter (0.95 ± 0.05 vs. 0.90 ± 0.07, P = 0.14).Conclusion: TIE index performance as weaning predictor was not different when calculated by two different measures with intra or inter-observers, confirming the reproducibility and clinical value of the method.FootnotesCite this article as: European Respiratory Journal 2019; 54: Suppl. 63, PA1138.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). ER -