RT Journal Article SR Electronic T1 Effects of respiratory muscle training with different modalities in COPD patients: A randomized controlled trial JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP PA2198 DO 10.1183/13993003.congress-2019.PA2198 VO 54 IS suppl 63 A1 Farias, Catharinne A1 Fregonezi, Guilherme A1 Batista, Ilsa Priscila A1 Castro, Lhara A1 Lopes, Natália A1 Gualdi, Lucien A1 Montemezzodayane, Dayane A1 Britto, Raquel R A1 Resqueti, Vanessa YR 2019 UL http://erj.ersjournals.com/content/54/suppl_63/PA2198.abstract AB We hypothesize that inspiratory muscle training with conical flow resistance load (IMTFRL-PowerBreath) or respiratory muscle endurance training with normocapnic hyperpnea (RMTNH-SpiroTiger) could offer additional effects in exercise capacity and dyspnea when associated to pulmonary rehabilitation (PR) in COPD patients. Patients with COPD were allocated in 3 groups: PR, PR+IMTFRL, and PR+RMTNH and training during 10-weeks (5/day week - 3 days of full program on Hospital and 2days of aerobic at home). The PR was standard for all group: health education, treadmill aerobic training with 70% of max ISWT speed and peripheral muscle strength training. The PR+IMTFRL group training with a loading of 35% MIP with 5% increase/week up to 80%. The PR+RMTNH group training with a bag equivalent to 50% VC, respiratory rate of 35 times of FEV1, increasing 2 to 3 minutes/week, up to 20 minutes. Outcomes including spirometry, respiratory muscle assessment (MIP, SPImax, SNIP, MEP), 6MWT and ISWT, dyspnea and fatigue were assessed. A total of 33 patients where include, age 66.2±4.9 yrs and BMI 28±4.3 kg/m2. The exercise capacity increased in the PR+IMTFRL and PR+RMTNH (p<0.0001) and was higher by ISWT in PR+RMTNH group vs. PR group (p<0.005). Dyspnea and fatigue reduced after 6MWT and ISWT, in all three groups (p<0.001). We also found an increase in MIP in all groups (p<0.0001), in SPImax in the PR+RMTFRL group (p<0.0001) and in SNIP in PR+RMTFRL and PR+RMTNH (p<0.0001). In PR+RMTNH group we observed an improvement in MEP (p<0.0001) in the PR group. The association of IMT or RMT to PR programs provided additional gains on exercise capacity, dyspnea, and fatigue in COPD patients.FootnotesCite this article as: European Respiratory Journal 2019; 54: Suppl. 63, PA2198.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).