RT Journal Article
SR Electronic
T1 EBUS Elastography in the diagnosis of lymphadenopathies: preliminary data from a single-centre experience
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP PA4777
DO 10.1183/13993003.congress-2019.PA4777
VO 54
IS suppl 63
A1 Elisa Clivati
A1 Giacomo Bonizzoni
A1 Davide Indellicati
A1 Aleksandar Veljkovic
A1 Luisella Righi
A1 Valter Bernardi
YR 2019
UL http://erj.ersjournals.com/content/54/suppl_63/PA4777.abstract
AB Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is widely used for nodal staging in lung cancer patients. Ultrasound elastography (UE) is a new sonographical analysis that translates tissue stiffness into a colour signal.Aim: to assess the value of UE in discriminating malignant from non-malignant mediastinal lymph nodes (LNs).Methods: We evaluated 32 LNs from 28 patients who underwent EBUS-TBNA from Oct 2018 to Feb 2019. EBUS indication, LNs location and UE measurements, such as strain ratio (SR) and blue colour proportion (BCP), were collected. LNs were classified as type 1, mainly non-blue; type 2, partially blue; type 3, mainly blue (stiffest tissues). We compared UE features with TBNA cytological results.Results: 18 patients underwent EBUS-TBNA for cancer staging. 12 LNs were located in group 7, 7 in 4R, 3 in 10R, 3 in 4L, 3 in 11R, 3 in 11L, 1 in 12R. 12 LNs were positive for malignancy, 20 LNs were negative, whose 9 sarcoidotic. BCP and SR were higher in positive LNs (BCP: 0.45 ± 0.19 vs 0.31 ± 0.16, p 0.04; SR: 79.8 ± 69.1 vs 47.4 ± 48.2, not significant). Comparing type 3 group (13 LNs) with the other groups we find that odds ratio for malignance was 6.0 (95% CI: 1.3 – 24.9; p 0.03).Conclusion: Along with CT, PET and EBUS imaging, UE could identify malignant involvement and guide the LNs sampling during EBUS-TBNA. Further studies are needed to validate this technique.FootnotesCite this article as: European Respiratory Journal 2019; 54: Suppl. 63, PA4777.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).