PT  - JOURNAL ARTICLE
AU  - Marina Barusso-Grüninger
AU  - Júlia Gianjoppe-Santos
AU  - Valéria Amorim Pires Di Lorenzo
TI  - Impact of different intensities of resistance training on health status focusing on activities of daily living in patients with COPD: randomized controlled study
AID  - 10.1183/13993003.congress-2019.OA5356
DP  - 2019 Sep 28
TA  - European Respiratory Journal
PG  - OA5356
VI  - 54
IP  - suppl 63
4099  - http://erj.ersjournals.com/content/54/suppl_63/OA5356.short
4100  - http://erj.ersjournals.com/content/54/suppl_63/OA5356.full
SO  - Eur Respir J2019 Sep 28; 54
AB  - Resistance training has been shown to reverse muscle dysfunction and enhance health status in patients with COPD. It is however not clear which is the optimal intensity of resistance training.Aim: To evaluate the effect of low-load/high-repetition (LL/HR) versus high-load/low-repetition (HL/LR) resistance training intensities on dyspnea during simulated ADL tasks, exercise capacity, muscle strength and quality of life.Methods: A randomized controlled trial was performed. Twenty-seven patients were randomized into LL/HR group (n=13, 10 male, 68.6±8.7 years, FEV1 49±16 %pred) and HL/LR group (n=14, 10 male, 69±6.8 years, FEV1 50.2±15 %pred). Patients performed chest press, high pulley, and leg press exercises. LL/HR initial load was set at 30% of 1-RM, and HL/LL was set at 60% of 1-RM. Outcomes were dyspnea during simulated ADL tasks, London Chest Activity of Daily Living Scale (LCADL), 6-minute walk distance (6MWD), shoulder flexor strength and Saint George’s Respiratory Questionnaire (SGRQ).Results: SGRQ symptoms improved significantly more in the LL/HR group (pre= 40.2±20; post=26.4±18, p=0.002) compared to HL/LR. No difference was found for the other outcomes. Dyspnea during ADL simulation (p=0.005), LCADL physical domain (p=0.005) and total score (p=0.013), 6MWD (p=0.023), and shoulder flexor strength (p<0.001) improved significantly in both groups.Conclusion: Our results suggest an equivalent improvement in ADL dyspnea and LCADL followed by improvements in exercise capacity and muscle strength after both LL/HR and HL/LR training. LL/HR training presented a superior effect on the SGRQ symptoms domain.FootnotesCite this article as: European Respiratory Journal 2019; 54: Suppl. 63, OA5356.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).