PT - JOURNAL ARTICLE AU - Mg Ramachandran AU - Siva Yuvarajan AU - Praveen Radhakrishnan AU - Antonius Maria Selvam AU - Gangi Reddy TI - Role Of Non Invasive Ventilation With Average Volume Assured Pressure Support (AVAPS)mode in patients with COPD and Type II Respiratory Failure AID - 10.1183/13993003.congress-2019.PA2298 DP - 2019 Sep 28 TA - European Respiratory Journal PG - PA2298 VI - 54 IP - suppl 63 4099 - http://erj.ersjournals.com/content/54/suppl_63/PA2298.short 4100 - http://erj.ersjournals.com/content/54/suppl_63/PA2298.full SO - Eur Respir J2019 Sep 28; 54 AB - Introduction: Non invasive ventilation in patients with respiratory failure was traditionally determined based on clinical assessment and changes in blood gas in arterial blood gas analysis with NIV support pressures that are manually adjusted. NIV BIPAP with AVAPS mode(Assured volume assisted pressure support mode)uses a fixed tidal volume that automatically adjusts to the patient need. Hence Our study is proposed to assess the use of NIV BIPAP with AVAPS mode in COPD patients with type II respiratory failure.Objectives: To evaluate the role of BIPAP AVAPS mode in COPD and compare with Conventional ST modeMethods: The study was carried out in Dept of pulmonary medicine.38 COPD patients with acute exacerberation and type II respiratory failure were included in the present study. Subjects were catagorised to two groups by block randomisation. Group 1 received NIV BIPAP with AVAPS mode, whereas group 2 received NIV BIPAP with conventional ST mode. Patients arterial gas values, heart rate, blood pressure, respiratory rate, maximum inspiratory postive airway pressure and expiratory positive airway pressure were measured 1 hour,6 hour and 24 hours based on the clinical status of the patients and values were compared.Results: we observed statistically significant difference in favour with BIPAP with AVAPS mode when compared ST mode in terms of PH(p=<0.001), PCO2(p=<0.038), Maximum inspiratory pressure(p <0.001), number of days in NIV(p=,0.001) and duration of hospital stay(p=<0.001).Conclusion: Thus BIPAP with AVAPS mode in NIV facilitates rapid recovery in pH, Pco2, and reduction in the number of days of hospitalisation when compared to conventional BIPAP STmode.FootnotesCite this article as: European Respiratory Journal 2019; 54: Suppl. 63, PA2298.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).