RT Journal Article SR Electronic T1 Dampness and mould at home and at work in the RHINE study: Increased onset and decreased remission of adult respiratory symptoms, asthma and rhinitis JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP OA485 DO 10.1183/13993003.congress-2019.OA485 VO 54 IS suppl 63 A1 Juan Wang A1 Mihkel Pindus A1 Christer Janson A1 Torben Sigsgaard A1 Jeong-Lim Kim A1 Mathias Holm A1 Johan Sommar A1 Hans Orru A1 Thorarin Gislason A1 Ane Johannessen A1 Randi J. Bertelsen Bertelsen A1 Dan Norbäck YR 2019 UL http://erj.ersjournals.com/content/54/suppl_63/OA485.abstract AB Aim: To study associations between dampness and mould at home and in the workplace buildings and onset and remission of respiratory symptoms, asthma and rhinitis among adults.Methods: Associations between dampness, mould and mould odour at home and at work and respiratory health were investigated in cohort of 11,506 adults from Iceland, Norway, Sweden, Denmark and Estonia in the RHINE study. They answered a questionnaire at baseline and ten years later, with questions on respiratory health and dampness problems at home and at work.Results: Baseline water damage, floor dampness, mould and mould odour at home were associated with onset of respiratory symptoms and asthma (ORs from 1.23 to 2.24). Dampness at home during follow up was associated with onset of respiratory symptoms, asthma and rhinitis (ORs from 1.21 to 1.52). Dampness at work during follow up was associated with onset of respiratory symptoms, asthma and rhinitis (ORs from 1.31 to 1.47). Combined dampness at home and at work increased the risk of onset of respiratory symptoms and rhinitis (ORs from 1.51 to 1.80). Dampness and mould at home and at work decreased remission of respiratory symptoms and rhinitis.Conclusions: Dampness and mould at home and in the workplace buildings can increase onset of respiratory symptoms, asthma and rhinitis, and decrease remission of respiratory symptoms and rhinitis among adults. Exposure to dampness both at home and at work can increase the risk of having respiratory symptoms, asthma and rhinitis. Our study adds new evidence on the health significance of dampness and mould from a prospective study.FootnotesCite this article as: European Respiratory Journal 2019; 54: Suppl. 63, OA485.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).