RT Journal Article
SR Electronic
T1 Evaluation of AHI agreement between PAP algorithms and polygraphy in CSA patients
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP PA823
DO 10.1183/13993003.congress-2019.PA823
VO 54
IS suppl 63
A1 Yann RETORY
A1 Shuo Liu
A1 Sébastien Hardy
A1 François Cottin
A1 Gabriel Roisman4
A1 Michel Petitjean
YR 2019
UL http://erj.ersjournals.com/content/54/suppl_63/PA823.abstract
AB Introduction: During continuous Positive Air Pressure (PAP) treatment, residual Apnea Hypopnea Index (AHI) determination relies only on Flow. Manufacturers use their own determinants to classify respiratory events and use different technologies (forced oscillation technique, pulse of pressure, cardiac oscillations, machine learning). Residual AHI from devices are challenged when compared to AASM compliant analysis (Li, Q. Y. et al. Sleep 2015; 38:597–605). There is still a need to investigate in reproducible conditions potential discrepancy in AHI because treatment efficacy often relies on it with Central Sleep Apnea (CSA) phenotypes.Aim: We aimed to compare AHI detection in several PAP devices by using bench test simulation of reproducible respiratory profile recorded in CSA patients by using polygraphy.Methods: We compared AHI, and related indices of CSA patients obtained with NoxT3 polygraph and from Airsense (Resmed), Sleepstyle (Fischer & Paykel), S.Box (Sefam) and Dreamstation (Philips). 26 hours of breathing profiles from three CSA patients containing 3133 respiratory events (1378 Apneas (59% Central), 1755 hypopneas) were characterized following AASM rules. Breathing profiles were simulated on a bench (Zhu, K. et al. Sleep Med Clin 2012; 12:517-527) including an artificial lung (ASL 5000) and a Starling resistor driven by a custom-made algorithm.Results: Comparisons revealed mild differences for global AHI whereas there was a tremendous underestimation of hypopnea rate (p<0.05, n=26).Conclusion: This study suggests that AHI from devices are underestimated in CSA patients. Particular attention would be required when considering treatment efficiency using flow based AHI.FootnotesCite this article as: European Respiratory Journal 2019; 54: Suppl. 63, PA823.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).