PT  - JOURNAL ARTICLE
AU  - Chawla, Gopal
AU  - Sharma, Vinod
AU  - Jain, Shubhra
AU  - Joshi, Vinod
AU  - Niwas, Ram
TI  - Osteoporosis and its relation with severity of COPD and steroids use
AID  - 10.1183/13993003.congress-2019.PA4301
DP  - 2019 Sep 28
TA  - European Respiratory Journal
PG  - PA4301
VI  - 54
IP  - suppl 63
4099  - http://erj.ersjournals.com/content/54/suppl_63/PA4301.short
4100  - http://erj.ersjournals.com/content/54/suppl_63/PA4301.full
SO  - Eur Respir J2019 Sep 28; 54
AB  - Introduction: Osteoporosis is one of the extrapulmonary effects of Chronic Obstructive Pulmonary Disease (COPD). Osteoporosis is characterized by low bone mineral density (BMD) resulting in an increased risk of fracture thereby causing significant morbidity and mortality.Aims and Objectives: To determine association between BMD and severity of COPD and association between steroid intake and bone mineral densityMaterial and Methods: 100 new COPD patients were recruited in this study. Diagnosis and severity grading of COPD patients were according to the GOLD guidelines. BMD (at the lumbar spine and at the femoral neck) was performed using Dual energy X-ray absorptiometry (DEXA). BMD was expressed in g/cm2 and standardized T-score and Z-score.Results:Conclusion: There was significant derangement in BMD and T-score in COPD patients which leads to osteoporosis and osteopenia. Patients with history of long term use of oral corticosteroids had more negative values of T –scores at both lumbar spine and femoral neck when compared to inhaled steroids. It is advised to screen for osteoporosis in COPD patients with long term steroid use and who had severe disease.FootnotesCite this article as: European Respiratory Journal 2019; 54: Suppl. 63, PA4301.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).