TY - JOUR T1 - Paediatric severe asthma: a need for novel innate molecular phenotypes JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.01459-2019 VL - 54 IS - 2 SP - 1901459 AU - Kristina Laubhahn AU - Bianca Schaub Y1 - 2019/08/01 UR - http://erj.ersjournals.com/content/54/2/1901459.abstract N2 - Asthma is a heterogeneous chronic inflammatory disease of the airways with variety of different phenotypes and is most frequently classified according to clinical phenotypes into allergic and non-allergic asthma [1] or according to severity into intermittent, mild, moderate or severe asthma [2]. Asthma affects around 14% of children worldwide and different immune cells and inflammatory mediators play a role, leading to typical asthma pathophysiology [3]. Severe asthma is associated with high mortality, morbidity and healthcare expense [4].Molecular phenotyping and mainstay treatment of children with severe asthma is a great challenge and requires further in depth studies http://bit.ly/2ME9GQP ER -