TY - JOUR T1 - Return of sleep apnoea and sleep fragmentation following CPAP withdrawal in patients with obstructive sleep apnoea JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.02351-2018 VL - 53 IS - 5 SP - 1802351 AU - Chris Turnbull AU - Saxon Pattenden AU - Thomas Gaisl AU - Valentina Rossi AU - Sira Thiel AU - Malcolm Kohler AU - John Stradling Y1 - 2019/05/01 UR - http://erj.ersjournals.com/content/53/5/1802351.abstract N2 - We previously published data in the European Respiratory Journal describing the return of obstructive sleep apnoea (OSA) following the withdrawal of continuous positive airway pressure (CPAP) [1]. In this study, about one third of patients did not experience a significant return of OSA by the fourth night without CPAP, as measured using the oxygen desaturation index (ODI). This suggested that CPAP need not be an every night therapy in some patients with OSA, although there was no clear way of identifying such patients in advance of the trial of CPAP withdrawal. Limitations to this study were discussed in the paper and correctly highlighted by van Zeller and Drummond [2].Following CPAP withdrawal, in some obstructive sleep apnoea patients, evidence of sleep fragmentation can occur prior to the appearance of significant oxygen desaturations http://ow.ly/OhoN30o957o ER -