TY - JOUR T1 - Changing prevalence of current asthma and inhaled corticosteroid treatment in the UK: population-based cohort 2006–2016 JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.02130-2018 VL - 53 IS - 4 SP - 1802130 AU - Chloe I. Bloom AU - Sejal Saglani AU - Johanna Feary AU - Debbie Jarvis AU - Jennifer K. Quint Y1 - 2019/04/01 UR - http://erj.ersjournals.com/content/53/4/1802130.abstract N2 - Asthma is the most common respiratory disorder in the UK, yet we have incomplete knowledge on the prevalence of current disease, treatment and exacerbations.We used UK electronic healthcare records, 2006–2016, to estimate the prevalence of current asthma by year, sex and age (<5, 5–11, 12–17, 18–24, 25–54 and ≥55 years), and the proportion prescribed inhaled corticosteroids (ICS) and additional asthma therapy, treated for exacerbations and other asthma care markers.Overall current asthma prevalence was 6.5% in 2016 (7.2% in 2006). Prevalence fell in those aged <45 years. The lowest prevalence and largest absolute decrease was in children aged <5 years. In 2016, 80% of current asthma patients were managed on ICS (65% in 2006); this increase occurred in all age groups, primarily due to an increase in low-dose ICS. During this time there was an increase in all age groups in the proportion prescribed additional asthma therapy, treated for an exacerbation within primary care and given an annual asthma review or management plan. Hospitalised exacerbations showed minimal change over time.Asthma remains highly prevalent and a significant healthcare burden. In those with a diagnosis, there was an increase in ICS prescriptions and treatment of exacerbations across all age groups. This may reflect a trend towards more aggressive asthma management within primary care. An apparent decline in prevalence was observed in those aged <45 years, particularly in children aged <5 years.Asthma management is changing, with increasing prescriptions of maintenance inhalers and oral corticosteroids. Disease prevalence is decreasing in those aged <45 years, with the most rapid decline found in preschool children. http://ow.ly/8g8D30nlBUW ER -