RT Journal Article SR Electronic T1 Nationwide cloud-based integrated database of idiopathic interstitial pneumonias for multidisciplinary discussion JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP 1802243 DO 10.1183/13993003.02243-2018 A1 Tomoyuki Fujisawa A1 Kazutaka Mori A1 Masashi Mikamo A1 Takashi Ohno A1 Kensuke Kataoka A1 Chikatoshi Sugimoto A1 Hideya Kitamura A1 Noriyuki Enomoto A1 Ryoko Egashira A1 Hiromitsu Sumikawa A1 Tae Iwasawa A1 Shoichiro Matsushita A1 Hiroaki Sugiura A1 Mikiko Hashisako A1 Tomonori Tanaka A1 Yasuhiro Terasaki A1 Shinobu Kunugi A1 Masashi Kitani A1 Ryo Okuda A1 Yasuoki Horiike A1 Yasunori Enomoto A1 Hideki Yasui A1 Hironao Hozumi A1 Yuzo Suzuki A1 Yutaro Nakamura A1 Junya Fukuoka A1 Takeshi Johkoh A1 Yasuhiro Kondoh A1 Takashi Ogura A1 Yoshikazu Inoue A1 Yoshinori Hasegawa A1 Naohiko Inase A1 Sakae Homma A1 Takafumi Suda YR 2019 UL http://erj.ersjournals.com/content/early/2019/03/06/13993003.02243-2018.abstract AB Multidisciplinary discussion (MDD) requiring close communication between specialists (clinicians, radiologists, and pathologists) is the gold standard for the diagnosis of idiopathic interstitial pneumonias (IIPs). However, MDD by specialists is not always feasible because they are often separated by time and location. An online database would facilitate data sharing and MDD. Our aims were to develop a nationwide cloud-based integrated database containing the clinical, radiologic, and pathological data of patients with IIPs along with a web-based MDD system and to validate the diagnostic utility of web-based MDD in IIPs.Clinical data, high-resolution computed tomography images, and lung biopsy slides from patients with IIPs were digitised and uploaded to separate servers to develop a cloud-based integrated database. Web-based MDD was performed using the database and video-conferencing to reach a diagnosis.The clinical, radiologic, and pathological data of 524 patients in 39 institutions were collected, uploaded, and incorporated into the cloud-based integrated database. Subsequently, web-based MDD with a pulmonologist, radiologist, and pathologist using the database and video conferencing were successfully performed for the 465 cases with adequate data. Overall, the web-based MDD changed the institutional diagnosis in 219 cases (47%). Notably, the MDD diagnosis yielded better prognostic separation among the IIPs than did the institutional diagnosis.This is the first study of developing nationwide cloud-based integrated database containing the clinical, radiologic, and pathological data for web-based MDD in patients with IIPs. The database and the web-based MDD system that we built made MDD more feasible in practice, potentially increasing accurate diagnosis of IIPs.FootnotesThis manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.Conflict of interest: Dr. Fujisawa has nothing to disclose.Conflict of interest: Dr. Mori has nothing to disclose.Conflict of interest: Dr. Mikamo has nothing to disclose.Conflict of interest: Dr. Ohno has nothing to disclose.Conflict of interest: Dr. Kataoka has nothing to disclose.Conflict of interest: Dr. Sugimoto has nothing to disclose.Conflict of interest: Dr. Kitamura has nothing to disclose.Conflict of interest: Dr. Enomoto has nothing to disclose.Conflict of interest: Dr. EGASHIRA has nothing to disclose.Conflict of interest: Dr. Sumikawa has nothing to disclose.Conflict of interest: Dr. Iwasawa has nothing to disclose.Conflict of interest: Dr. Matsushita has nothing to disclose.Conflict of interest: Dr. Sugiura reports and receives honorarai for consultancy services from Ono Pharmaceutical Co., Ltd, Bristol-Myers Squibb K. K., and MSD K. K..Conflict of interest: Dr. Hashisako has nothing to disclose.Conflict of interest: Dr. TANAKA has nothing to disclose.Conflict of interest: Yasuhiro TerasakiConflict of interest: Dr. Kunugi has nothing to disclose.Conflict of interest: Dr. Kitani has nothing to disclose.Conflict of interest: Dr. Okuda has nothing to disclose.Conflict of interest: Dr. Horiike has nothing to disclose.Conflict of interest: Dr. Yasui has nothing to disclose.Conflict of interest: Dr. Hozumi has nothing to disclose.Conflict of interest: Dr. Suzuki has nothing to disclose.Conflict of interest: Dr. Nakamura has nothing to disclose.Conflict of interest: Dr. Fukuoka has nothing to disclose.Conflict of interest: Dr. Johkoh has nothing to disclose.Conflict of interest: Dr. Kondoh has nothing to disclose.Conflict of interest: Dr. Ogura has nothing to disclose.Conflict of interest: Dr. Inoue reports other from Boehringer Ingelheim, outside the submitted work.Conflict of interest: Dr. Hasegawa has nothing to disclose.Conflict of interest: Dr. Inase has nothing to disclose.Conflict of interest: Dr. Homma has nothing to disclose.Conflict of interest: Dr. Suda has nothing to disclose.