PT - JOURNAL ARTICLE AU - Tomoyuki Fujisawa AU - Kazutaka Mori AU - Masashi Mikamo AU - Takashi Ohno AU - Kensuke Kataoka AU - Chikatoshi Sugimoto AU - Hideya Kitamura AU - Noriyuki Enomoto AU - Ryoko Egashira AU - Hiromitsu Sumikawa AU - Tae Iwasawa AU - Shoichiro Matsushita AU - Hiroaki Sugiura AU - Mikiko Hashisako AU - Tomonori Tanaka AU - Yasuhiro Terasaki AU - Shinobu Kunugi AU - Masashi Kitani AU - Ryo Okuda AU - Yasuoki Horiike AU - Yasunori Enomoto AU - Hideki Yasui AU - Hironao Hozumi AU - Yuzo Suzuki AU - Yutaro Nakamura AU - Junya Fukuoka AU - Takeshi Johkoh AU - Yasuhiro Kondoh AU - Takashi Ogura AU - Yoshikazu Inoue AU - Yoshinori Hasegawa AU - Naohiko Inase AU - Sakae Homma AU - Takafumi Suda TI - Nationwide cloud-based integrated database of idiopathic interstitial pneumonias for multidisciplinary discussion AID - 10.1183/13993003.02243-2018 DP - 2019 Jan 01 TA - European Respiratory Journal PG - 1802243 4099 - http://erj.ersjournals.com/content/early/2019/03/06/13993003.02243-2018.short 4100 - http://erj.ersjournals.com/content/early/2019/03/06/13993003.02243-2018.full AB - Multidisciplinary discussion (MDD) requiring close communication between specialists (clinicians, radiologists, and pathologists) is the gold standard for the diagnosis of idiopathic interstitial pneumonias (IIPs). However, MDD by specialists is not always feasible because they are often separated by time and location. An online database would facilitate data sharing and MDD. Our aims were to develop a nationwide cloud-based integrated database containing the clinical, radiologic, and pathological data of patients with IIPs along with a web-based MDD system and to validate the diagnostic utility of web-based MDD in IIPs.Clinical data, high-resolution computed tomography images, and lung biopsy slides from patients with IIPs were digitised and uploaded to separate servers to develop a cloud-based integrated database. Web-based MDD was performed using the database and video-conferencing to reach a diagnosis.The clinical, radiologic, and pathological data of 524 patients in 39 institutions were collected, uploaded, and incorporated into the cloud-based integrated database. Subsequently, web-based MDD with a pulmonologist, radiologist, and pathologist using the database and video conferencing were successfully performed for the 465 cases with adequate data. Overall, the web-based MDD changed the institutional diagnosis in 219 cases (47%). Notably, the MDD diagnosis yielded better prognostic separation among the IIPs than did the institutional diagnosis.This is the first study of developing nationwide cloud-based integrated database containing the clinical, radiologic, and pathological data for web-based MDD in patients with IIPs. The database and the web-based MDD system that we built made MDD more feasible in practice, potentially increasing accurate diagnosis of IIPs.FootnotesThis manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.Conflict of interest: Dr. Fujisawa has nothing to disclose.Conflict of interest: Dr. Mori has nothing to disclose.Conflict of interest: Dr. Mikamo has nothing to disclose.Conflict of interest: Dr. Ohno has nothing to disclose.Conflict of interest: Dr. Kataoka has nothing to disclose.Conflict of interest: Dr. Sugimoto has nothing to disclose.Conflict of interest: Dr. Kitamura has nothing to disclose.Conflict of interest: Dr. Enomoto has nothing to disclose.Conflict of interest: Dr. EGASHIRA has nothing to disclose.Conflict of interest: Dr. Sumikawa has nothing to disclose.Conflict of interest: Dr. Iwasawa has nothing to disclose.Conflict of interest: Dr. Matsushita has nothing to disclose.Conflict of interest: Dr. Sugiura reports and receives honorarai for consultancy services from Ono Pharmaceutical Co., Ltd, Bristol-Myers Squibb K. K., and MSD K. K..Conflict of interest: Dr. Hashisako has nothing to disclose.Conflict of interest: Dr. TANAKA has nothing to disclose.Conflict of interest: Yasuhiro TerasakiConflict of interest: Dr. Kunugi has nothing to disclose.Conflict of interest: Dr. Kitani has nothing to disclose.Conflict of interest: Dr. Okuda has nothing to disclose.Conflict of interest: Dr. Horiike has nothing to disclose.Conflict of interest: Dr. Yasui has nothing to disclose.Conflict of interest: Dr. Hozumi has nothing to disclose.Conflict of interest: Dr. Suzuki has nothing to disclose.Conflict of interest: Dr. Nakamura has nothing to disclose.Conflict of interest: Dr. Fukuoka has nothing to disclose.Conflict of interest: Dr. Johkoh has nothing to disclose.Conflict of interest: Dr. Kondoh has nothing to disclose.Conflict of interest: Dr. Ogura has nothing to disclose.Conflict of interest: Dr. Inoue reports other from Boehringer Ingelheim, outside the submitted work.Conflict of interest: Dr. Hasegawa has nothing to disclose.Conflict of interest: Dr. Inase has nothing to disclose.Conflict of interest: Dr. Homma has nothing to disclose.Conflict of interest: Dr. Suda has nothing to disclose.