RT Journal Article SR Electronic T1 Development and validation of a simple tool for the assessment of home noninvasive ventilation: the S3-NIV questionnaire JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP 1801182 DO 10.1183/13993003.011822018 VO 52 IS 5 A1 Elise Dupuis-Lozeron A1 Grégoire Gex A1 Patrick Pasquina A1 Pierre-Olivier Bridevaux A1 Jean-Christian Borel A1 Paola M. Soccal A1 Wolfram Windisch A1 Jean-Louis Pépin A1 Jean-Paul Janssens A1 Dan Adler YR 2018 UL http://erj.ersjournals.com/content/52/5/1801182.abstract AB Patient-centred outcomes are significantly modified by long-term home noninvasive ventilation (NIV), but a short, self-administered, specific tool for routine clinical assessment is lacking. The aim of this study was to develop and validate the S3-NIV questionnaire, a short questionnaire to measure respiratory symptoms, sleep quality and NIV-related side effects.Patients with stable disease who were under long-term home NIV were recruited from three outpatient NIV services. Questionnaire development consisted of a selection of core items for analysis, followed by item reduction, validation and test–retest reliability.338 patients completed a 22-item questionnaire. 11 items were removed because of non-scalability (n=2), redundancy (n=8) and lack of fit (n=1). The final version of the S3-NIV questionnaire consisted of 11 items covering two dimensions: “respiratory symptoms” (Cronbach's α=0.84) and “sleep & NIV-related side effects” (Cronbach's α=0.77). Convergent validity was high between the “respiratory symptoms” subscale of the S3-NIV questionnaire and the St George's Respiratory Questionnaire (rho= −0.76, p<0.001), and between the “sleep & NIV-related side effects” subscale and the Quebec Sleep Questionnaire (rho=0.51, p<0.001). The S3-NIV questionnaire had good test­–retest reliability after 4 weeks (intraclass correlation coefficient=0.72).The S3-NIV questionnaire is a short, valid and repeatable self-completed tool for the routine clinical assessment of patients undergoing home NIV.The S3-NIV questionnaire provides clinicians and patients with a simple and reliable tool to assess important domains (symptoms, sleep quality and NIV-related side effects) as a complement to physiological monitoring http://ow.ly/rR8e30mKGCG