RT Journal Article SR Electronic T1 The risk of repeated hospitalizations for exacerbations of chronic obstructive pulmonary disease JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP PA920 DO 10.1183/13993003.congress-2018.PA920 VO 52 IS suppl 62 A1 Rustem Khamitov A1 Alfia Iakupova A1 Aigoul Zinnatullina YR 2018 UL http://erj.ersjournals.com/content/52/suppl_62/PA920.abstract AB Severe exacerbations of chronic obstructive pulmonary disease (COPD) are associated with fatal outcomes, especially in patients in need of hospitalizations. Repeated hospitalizations increase the economic burden of COPD.Objective: identification of the risk factors for repeated hospital admissions of patients with COPD, assessing the possibility of their modification.Methods: a retrospective analysis of case records of all patients admitted in the city hospital with exacerbations of COPD during 18 calendar months (161), of which 118 patients were hospitalized once, 14 - twice, and 5 - three times.Results: During inpatient treatment defects of therapy were detected: bronchodilator therapy (excessive theophylline), antimicrobial therapy and oxygen therapy (noncompliance, insufficient control of effects). Inhalation steroids were recommended excessively, with increasing frequency after each subsequent discharge. There was no control of adherence to treatment in outpatient settings. Significant risk factors for repeated hospitalizations were identified: male sex (RR 2,29; 95% CI; 0,78-6,69), age >70 years (RR 2,069; 95% CI; 1,01-4,2), smoking experience >40 years (RR 5,3; 95% CI; 1,6-17,5), duration of COPD >6 years (RR 2,4; 95% CI; 0,98-6,18), the presence of three or more concomitant diseases, first of all, cardiovascular (RR 13,0; 95% CI; 1,89-90,14).Conclusions: to reduce the risk of repeated hospitalizations, the main emphasis of treatment and prophylaxis should be directed to patients of working age: early smoking cessation, adequate treatment of COPD exacerbations and comorbidity in the hospital, control of adherence to treatment after discharge.FootnotesCite this article as: European Respiratory Journal 2018 52: Suppl. 62, PA920.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).