TY - JOUR T1 - Echocardiographic assessment in lowlanders vs. highlanders living above 2500m JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2018.PA3325 VL - 52 IS - suppl 62 SP - PA3325 AU - Mona Lichtblau AU - Stéphanie Saxer AU - Patrick Bader AU - Michael Furian AU - Philipp Scheiwiller AU - Maamed Mademilov AU - Bermet Estebesova AU - Batyr Osmonov AU - Nuriddin Marazhapov AU - Ulan Sheraliev AU - Talant Sooronbaev AU - Konrad Bloch AU - Silvia Ulrich Y1 - 2018/09/15 UR - http://erj.ersjournals.com/content/52/suppl_62/PA3325.abstract N2 - Background: High altitude pulmonary hypertension (PH) may chronically affect residents born and living above 2500m. We compared echocardiographic indices of cardiac function in highlanders (HL) and healthy lowlanders (LL).Methods: Data from an ongoing cohort study was evaluated. Left and right heart function of LL (living <800m) and HL (living ≥2500m asl, Kyrgyzstan) was assessed by standard Doppler echocardiography including assessment of tricuspid pressure to estimate PH.Results: 129 participants were measured mean±SD: LL: males/females(m/f) 19/13, age 41.9±8.6yrs, BMI 27.2±4.3kg/m2; HL: m/f 49/48, age 48.8±11.6yrs, BMI 27.1±4.3kg/m2. See table 1 for echocardiography. View this table:Conclusion: Chronic exposure to hypoxia in HL promotes a rise in pulmonary artery pressure and a decreased right heart function compared to LL.FootnotesCite this article as: European Respiratory Journal 2018 52: Suppl. 62, PA3325.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). ER -