RT Journal Article SR Electronic T1 Sarcopenia index correlates with COPD clinical outcomes. JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP PA722 DO 10.1183/13993003.congress-2018.PA722 VO 52 IS suppl 62 A1 Carlos Antonio Amado Diago A1 Beatriz Abascal Bolado A1 Juan Agüero Calvo A1 Begoña Durantes A1 Milagros Ruiz De Infante A1 Armando Raúl Guerra A1 María Teresa García-Unzueta A1 Bernardo Alio Lavín A1 Elena Arnaiz-García YR 2018 UL http://erj.ersjournals.com/content/52/suppl_62/PA722.abstract AB Muscle mass is an important risk factor for poor outcomes in COPD. The sarcopenia index (SI) (serum creatinine value/cystatin C value) X100 is a novel blood test to approximate muscle mass. The objective of this study is to analyze the correlation between Sarcopenia index (SI) and different COPD Outcomes.SI was calculated in 56 COPD patients from january 2016 to january 2017. Body Mass Index (BMI), Fat free Mass Index (FFMI), FEV1, Dyspnoea (mMRC), number of exacerbations in the previous year, number of exacerbations needing hospitalization, COPD Assessment Test (CAT) score and Six minute Walking test (6MWT) distance (m) were measured in these patients.Mean+/-Standard deviation age, BMI, FEV1, CAT, FFMI and 6MWT were respectively 66,8+/-7,3, 28,1+/-5,6 kg/m2, 53,4+/-17% 14+/-8 points, 18,7+/-2,4 Kg/m2 and 400+/-119. 75% were men. Mean SI was 89+/-20,5. SI correlates positively with FEV1 Pearson 0,495 p<0,001, 6MWT Pearson 0,603 (p<0,001), and negatively with CAT Pearson-0,387 (p=0,009), mMRC Spearman -0,379 (p=0,004), number of exacerbations in the previous 12 months Spearman -0,383 p=0,004 and hospitalization in the previous 12 months Spearman -0,531 (p<0,001). Curiously, no statistically significant correlations were found with FFMI (p=0,148) or BMI (p=0,425).In conclusion SI is a promising tool for COPD that correlates with several relevant clinical outcomes.FootnotesCite this article as: European Respiratory Journal 2018 52: Suppl. 62, PA722.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).