PT  - JOURNAL ARTICLE
AU  - Joren Buekers
AU  - Jean-Marie Aerts
AU  - Jan Theunis
AU  - Anouk Vaes
AU  - Emiel Wouters
AU  - Martijn Spruit
AU  - Patrick De Boever
TI  - Multi-night continuous nocturnal oxygen saturation measurements in patients with COPD
AID  - 10.1183/13993003.congress-2018.PA4054
DP  - 2018 Sep 15
TA  - European Respiratory Journal
PG  - PA4054
VI  - 52
IP  - suppl 62
4099  - http://erj.ersjournals.com/content/52/suppl_62/PA4054.short
4100  - http://erj.ersjournals.com/content/52/suppl_62/PA4054.full
SO  - Eur Respir J2018 Sep 15; 52
AB  - Nocturnal oxygen desaturation is common in patients with COPD. Based on single-night oxygen saturation (SpO2) measurements, patients are considered a desaturator (cumulative time spent with SpO2 below 90% (CT90) ≥ 30%) or non-desaturator (CT90 < 30%). To date, it remains unknown whether nocturnal SpO2 profiles are comparable between multiple consecutive nights in COPD patients. Twelve COPD patients (nine male; age: 65 ± 6 years; FEV1: 44 ± 13 %predicted) without long-term oxygen therapy performed nocturnal SpO2 measurements during one week (Nonin WristOx2; 1 Hz). CT90 values were determined for every night separately, and for every patient, the average SpO2 and desaturation time (average duration of consecutive SpO2 values below 90%) were calculated. Patients performed SpO2 measurements for 6.5 (± 0.6) nights. Three patient profiles could be identified: consistent desaturators (CT90 ≥ 30% for every night; n=4), occasional desaturators (nights with CT90 ≥ 30% and nights with CT90 < 30%; n=6) and non-desaturators (CT90 < 30% for every night; n=2). The average SpO2 for consistent desaturators ranged between 82.5%-88.8%, and between 89.5%-90.7% for occasional desaturators. Non-desaturators had average values between 91.9%-93.2%. Average desaturation time was shorter for occasional desaturators (21-63 seconds) compared to consistent desaturators (77-3881 seconds). Based on single-night SpO2 measurements, occasional desaturators could be considered a desaturator or non-desaturator. Analysis of multi-night SpO2 measurements allowed us to make a distinction between consistent desaturators, occasional desaturators and non-desaturators.FootnotesCite this article as: European Respiratory Journal 2018 52: Suppl. 62, PA4054.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).