TY - JOUR T1 - Clinical peculiarities of seasonal respiratory allergy in children JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2018.PA4467 VL - 52 IS - suppl 62 SP - PA4467 AU - Olena Kuznietsova AU - Svitlana Nedelska Y1 - 2018/09/15 UR - http://erj.ersjournals.com/content/52/suppl_62/PA4467.abstract N2 - Background: Pollens and fungal spores are main causitive aeroallergens in bronchial asthma (BA) and allergic rhinitis (AR) symptoms in children of South region of Ukraine.Methods: Сlinical symptoms of AR and BA were analised in 154 children (mean age 12,3±0,27), 100 patients have pollen-mold co-sensitization (1st group) according to skin prick test results, in 54 patients isolated pollen allergy was present (2nd group). Skin prick testing, aerobiological sampling with Burkard trap was made. Evaluation of quality of life according to SF-36 questionnaire was conducted.Results: Aerobiological sampling showed that spores of Cladosporium (69%) and Alternaria (8,3% from total spore concentration) spp. predominate in outdoor air (March - November period). Among pollens Ragweed grains are the main species (71%) that present in the air from August to October.Seasonal nasal and/or conjunctive symptoms in 2/3 of patients (66,7%) of 1st group disturb their daily activity and/or sleep. In 2nd group mild symptoms dominate (53,7%, р<0,05). BA was predominantly uncontrolled in 90% children with pollen-mold sensitization and just in 51% (р<0,05) in comparative group. Uncontrolled course of BA was associated with allergy to Cladosporium, Alternaria and Aspergillus. BA exacerbation duration in patients of 1st group was 2,36±0,89 weeks, among 2nd group - 1,45±0,63 weeks (р<0,05). Correlation of rhinitis symptoms (by daily diary questions) with pollen and spores air concentration was revealed (Spirman r=+0,67-0,85, p<0.05) with 1-2 days delay.Conclusion: Presence of mold hypersensitivity in children determines more severe nasal and bronchial symptoms, lower asthma control and prolonged exacerbation (p<0,05).FootnotesCite this article as: European Respiratory Journal 2018 52: Suppl. 62, PA4467.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). ER -