RT Journal Article
SR Electronic
T1 Pulmonary vascular disease(PC) and risk of mortality in patients with idiopathic pulmonary fibrosis(IPF)
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP OA3806
DO 10.1183/13993003.congress-2018.OA3806
VO 52
IS suppl 62
A1 Elena Rodriguez Jimeno
A1 Fernando Pedraza Serrano
A1 Alicia Oliva Ramos
A1 Gema Sánchez Muñoz
A1 Virginia Gallo González
A1 Rodrigo Jiménez García
A1 Ana López De Andrés
A1 Valentín Hernández Barrera
A1 Luis Puente Maestu
A1 Javier De Miguel Díez
YR 2018
UL http://erj.ersjournals.com/content/52/suppl_62/OA3806.abstract
AB Introduction: IPF may be associated with various comorbidities, including pulmonary vascular disorders, especially thromboembolism and pulmonary hypertension. The aim of this study was to assess the influence of PC diseases on the intra-hospital mortality of patients hospitalized with the diagnosis of IPF in Spain(2002-2014).Methods: It is a retrospective and observational study using data from the CMBD (Minimum Data Set) developed by the Ministry of Health of Spain. Patients with IPF (IPF group) were compared with controls without this disease (No-FPI group) matched by age, sex, city and year. Comorbidity was assessed using the Elixhauer index, which specifically includes the existence of PC diseases. In-hospital mortality was also collected.Results: There were 10285 patients with IPF and 10285 controls, with a mean age of 73.68±11 years and a majority of males (57.23%). The prevalence of CP diseases was 14.94% in the IPF group and 4.23% in the No-IPF group (p <0.01). In the first group, an increase in the prevalence of PC diseases was observed over time, from 11.76% in 2012 to 15.45% in 2014 (p <0.01). Mortality was 13.02% in the IPF group compared to 7.76% in the non-IPF group (p <0.01). In the logistic regression analysis, it was observed that the presence of PC diseases was an independent risk factor of in-hospital mortality (OR 1.45, 95% CI 1.19-1.77).Conclusions: The presence of PC diseases is more common in patients admitted with IPF than in controls without this disease and has increased over time in the first group. Patients admitted with IPF who have PC diseases have a higher risk of death during hospital admission than those without this comorbidity.FootnotesCite this article as: European Respiratory Journal 2018 52: Suppl. 62, OA3806.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).