PT  - JOURNAL ARTICLE
AU  - Darine Sakka
AU  - Hanen Smadhi
AU  - Achraf Ben Tkhayat
AU  - Hela Kamoun
AU  - Ines Akrout
AU  - Dorra Greb
AU  - Hajer Ben Abdelghaffar
AU  - Hela Hassan
AU  - Leila Elfekih
AU  - Mohamed Lamine Megdiche
TI  - Mediastinal masses: Clinical, radiological and pathological analysis
AID  - 10.1183/13993003.congress-2018.PA2579
DP  - 2018 Sep 15
TA  - European Respiratory Journal
PG  - PA2579
VI  - 52
IP  - suppl 62
4099  - http://erj.ersjournals.com/content/52/suppl_62/PA2579.short
4100  - http://erj.ersjournals.com/content/52/suppl_62/PA2579.full
SO  - Eur Respir J2018 Sep 15; 52
AB  - Introduction: Mediastinal masses are frequent and characterized by clinical variability and histological diversity. Etiological diagnosis requires a rigorous approach.Aims: Analyze epidemiological, clinical, imaging and pathology data of patients with mediastinal mass, relating them with anatomical location.Methods: Medical records of patients referred by mediastinal mass between January 2006 and December 2017 were reviewed.Results: We reviewed records from 120 patients, 58% females, mean age 48+/-16.8 years. Most frequent complaints were dyspnea (36.8%), chest pain (22.6%) and cough (18.9%). Chest radiograph was normal in 15%. In 24.3% the mass was an unexpected finding on radiological examinations. Pathological diagnosis was obtained by surgery (30%), CT Scan guided needle biopsy (18%) or mediastinoscopy (20%). Masses located superiorly were most frequently associated with dyspnea and cough. Most causes were thymomas (20%), lymphomas (18%) and cystic lesions (10%). Most frequent causes of anterior, middle, posterior and superior masses were, respectively: thymoma (26%), cystic lesions (12.2%), neurogenic tumor (55%) and lymphoma (24.2 %). Surgical treatment was indicated in 30%.Conclusion: Most mediastinal masses were thymomas and lymphomas. Mediastinal masses were, quite often, an unexpected finding. They constitute often a diagnostic challenge. CT scan is essential in the etiological investigation. Histological evidence is mandatory directing the therapeutic attitude.FootnotesCite this article as: European Respiratory Journal 2018 52: Suppl. 62, PA2579.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).