PT  - JOURNAL ARTICLE
AU  - Takao Miyoshi
AU  - Wakaba Furuie
AU  - Yoshio Otani
AU  - Chihiro Tani
AU  - Marika Waku
AU  - Fumika Koike
AU  - Yasunari Miyazaki
AU  - Naohiko Inase
AU  - Tetsuo Sasano
AU  - Miho Akaza
AU  - Tetsuo Kubota
AU  - Yuki Sumi
TI  - Can air purifier promote the indoor cleanliness and improve the patients with asthma?
AID  - 10.1183/13993003.congress-2018.PA1691
DP  - 2018 Sep 15
TA  - European Respiratory Journal
PG  - PA1691
VI  - 52
IP  - suppl 62
4099  - http://erj.ersjournals.com/content/52/suppl_62/PA1691.short
4100  - http://erj.ersjournals.com/content/52/suppl_62/PA1691.full
SO  - Eur Respir J2018 Sep 15; 52
AB  - Introduction: In the previous work about infantile asthma, asthmatic symptoms improved by cleaning the indoor air quality using air purifiers. However, there were few papers showing that adult patients with asthma had improved by the use of air purifiers in Japan.Objective: We aimed to find out whether air purifier improve indoor enviroment and the patients with asthma.Methods: Fifty patients with asthma, who had serum IgE antigen specific for house dust mite, were enrolled and randomly divided into intervention group (n = 30) and control group (n = 20). Patients in the intervention group used air purifiers in their bedrooms. Before and after the use of air purifiers, we measured the amount of house dust mite antigens, fungi, and fine particles with a diameter of 2.5 μm or less (PM2.5) to evaluate indoor air quality. The statuses of asthma were evaluated objectively by pulmonary function tests, FOT, and FeNO. Clinical assessment of asthma control were evaluated by ACT score and treatment steps.Results: Significant differences by the intervention were observed in the amount of PM2.5 in the bedroom and FeNO. Some other parameters in the intervention group showed better results (Figure.1), however, the differences from control group did not reach significant level.Conclusion: Indoor cleaning by air purifier seems promising therapeutic option for patients with asthma and further study is needed to clarify it’s roles.Figure.1FootnotesCite this article as: European Respiratory Journal 2018 52: Suppl. 62, PA1691.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).