TY - JOUR T1 - Smoking and severe persistent asthma JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2018.PA1230 VL - 52 IS - suppl 62 SP - PA1230 AU - Paraskevi Katsaounou AU - Mikaela Odemyr AU - Otto Spranger AU - Anne Lindberg AU - Michael E Hyland AU - Μatthias Gasser AU - Michael Larbig AU - Ioannis Kottakis AU - Xavier Jaumont AU - Ismail Kasujee Y1 - 2018/09/15 UR - http://erj.ersjournals.com/content/52/suppl_62/PA1230.abstract N2 - Smoking has detrimental effects on different clinical aspects of asthma, like accelerated decline in lung function, diminished symptom control, worse quality of life(QoL) and impaired therapeutic response. Fighting for Breath, a survey conducted by EFA(2005) showed that a worrying number of uncontrolled asthmatic patients(pts) indicated exposure to passive smoking as possible reason for poor QoL. After a decade, we conducted Still Fighting for Breath(GfK on behalf of Novartis upon EFA's invitation), an online survey in 1333 pts with severe persistent asthma(SPA) to assess the impact of SPA on pts’ daily life(fig1). Though law banning smoking in public spaces is implemented, still a high proportion of pts(88%) reported disruption in activities of daily living with 38% presenting poor perception of their disease control(disconnect b/w Pts perception and GINA assessment). Asthmatics identified exposure to smoking as trigger for exacerbations, with 63% of them(68% of caregivers) avoiding smoky premises. Percentage of smokers with SPA was higher than the general population in some of the countries. Current smokers with asthma were significantly more frequently diagnosed with anxiety(47%) and depression (41%) than never-smokers(40% and 27%, resp.) and ex-smokers(42% and 28%, resp.)(z-test, Α = 0.05). Thus, there is a need for improved management and support(smoking cessation, treatment, assessment of perception and psychological conditions) of asthmatic smokers with SPA.FootnotesCite this article as: European Respiratory Journal 2018 52: Suppl. 62, PA1230.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). ER -