RT Journal Article SR Electronic T1 The impact of smoking status on obstructive sleep apnea (OSA) severity. JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP PA4356 DO 10.1183/13993003.congress-2018.PA4356 VO 52 IS suppl 62 A1 Piotr Bielicki A1 Anna Trojnar A1 Piotr Sobieraj YR 2018 UL http://erj.ersjournals.com/content/52/suppl_62/PA4356.abstract AB Background: Smoking is a risk factor for obstructive sleep apnea (OSA), however, little is known about the impact of smoking on OSA symptoms.Aim: Analysis of OSA severity in relation to smoking status.Material and methods: We enrolled consecutive patients referred to our outpatient clinic between 2007 and 2017 due to snoring and sleepiness and in whom OSA was confirmed in polysomnography. The Epworth Sleepiness Scale (ESS) was used to evaluate daytime somnolence. A self-administered questionnaire was used to assess smoking status. Current smoking was defined as smoking of any amount of nicotine containing products such as cigarettes, cigars etc. Patients who had not smoked for at least 50 weeks were considered non-smokers. All parameters were assessed prior to the onset of any OSA treatment.Results: The study included 3613 patients with OSA (1016 F, 2597 M) with a mean ESS score of 11.1±5.5 points. Of these 796 (22%) were current smokers. This group was characterized by a larger proportion of men (77.9% vs 70.2%, p<0.005), younger age and higher AHI, ESS score and mean SpO2 during sleep. The comparison between the two groups is shown below:Current smoker Non-smokers pAge [years] 53.8±8.0 58.6±9.5 <0.001BMI [kg/m2 ] 31.5±6.3 31.5±5.8 nsESS 11.7±5.5 11.0±5.5 <0.001AHI [n per hour] 31.9±25.8 29.2±22.6 <0.05BMI – body mass index, ESS - Epworth Sleepiness Scale score, AHI- apnea-hypopnea index, ns – not significantConclusions: Our results suggest that active smokers may develop OSA earlier and OSA in current smokers may be more severe.FootnotesCite this article as: European Respiratory Journal 2018 52: Suppl. 62, PA4356.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).