TY - JOUR T1 - Detection of mild cognitive impairment in middle-aged and older adults with obstructive sleep apnoea JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.01137-2018 VL - 52 IS - 5 SP - 1801137 AU - Katia Gagnon AU - Andrée-Ann Baril AU - Jacques Montplaisir AU - Julie Carrier AU - Sirin Chami AU - Serge Gauthier AU - Chantal Lafond AU - Jean-François Gagnon AU - Nadia Gosselin Y1 - 2018/11/01 UR - http://erj.ersjournals.com/content/52/5/1801137.abstract N2 - Obstructive sleep apnoea increases the risk for mild cognitive impairment and dementia. The present study aimed to characterise the ability of two cognitive screening tests, the Mini-Mental State Examination and the Montreal Cognitive Assessment, to detect mild cognitive impairment in adults aged 55–85 years with and without obstructive sleep apnoea.We included 42 subjects with mild and 67 subjects with moderate-to-severe obstructive sleep apnoea. We compared them to 22 control subjects. Mild cognitive impairment was diagnosed by a comprehensive neuropsychological assessment. We used receiver operating characteristic curves to assess the ability of the two screening tests to detect mild cognitive impairment.The two screening tests showed similar discriminative ability in control subjects. However, among the mild and the moderate-to-severe obstructive sleep apnoea groups, the Mini-Mental State Examination was not able to correctly identify subjects with mild cognitive impairment. The Montreal Cognitive Assessment's discriminant ability was acceptable in both sleep apnoea groups and was comparable to what was observed in controls.The Mini-Mental State Examination should not be used to screen for cognitive impairment in patients with obstructive sleep apnoea. The Montreal Cognitive Assessment could be used in clinical settings. However, clinicians should refer patients for neuropsychological assessment when neurodegenerative processes are suspected.The Montreal Cognitive Assessment performs better than the Mini-Mental State Examination in detecting cognitive impairment in individuals with obstructive sleep apnoea http://ow.ly/8gLS30lxjZk ER -