TY - JOUR T1 - Experimental social rejection increases dyspnoea perception and neural processing of respiratory sensations in healthy subjects JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.01409-2018 SP - 1801409 AU - Michaela Herzog AU - Josef Sucec AU - Milica Vukovic AU - Ilse Van Diest AU - Omer Van den Bergh AU - Andreas von Leupoldt Y1 - 2018/01/01 UR - http://erj.ersjournals.com/content/early/2018/10/11/13993003.01409-2018.abstract N2 - Patients suffering from dyspnoea frequently report social rejection as a severe limitation of their lives [1]. While the effects of different social challenges on the respiratory system are already established in animal models [2, 3], little is known about potential consequences of social rejection on the perception and neural processing of dyspnoea in humans. Detrimental effects of social rejection are well documented for other aversive somatic symptoms [4, 5]. The current study examined whether social rejection would increase perceived dyspnoea and whether this would be paralleled by increased neural processing of respiratory sensations as measured with respiratory-related evoked potentials (RREPs) in the electroencephalogram (EEG).FootnotesThis manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.Conflict of interest: Dr. Herzog has nothing to disclose.Conflict of interest: Dr. Sucec has nothing to disclose.Conflict of interest: Dr. Vukovic has nothing to disclose.Conflict of interest: Dr. Van Diest has nothing to disclose.Conflict of interest: Dr. Van den Bergh has nothing to disclose.Conflict of interest: Dr. von Leupoldt reports grants from Research Fund KU Leuven, grants from Research Fund KU Leuven, grants from Herculesstichting, grants from Methusalem grant, during the conduct of the study. ER -