TY - JOUR T1 - The association of cardiovascular autonomic dysfunction and the prediction of COPD can be explained by neurohumoral activation JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.00737-2018 VL - 51 IS - 6 SP - 1800737 AU - Stefan Andreas Y1 - 2018/06/01 UR - http://erj.ersjournals.com/content/51/6/1800737.abstract N2 - I read with great interest the recent work by Ricci et al. [1] published in the European Respiratory Journal. This insightful population-based study followed a very large cohort without baseline airflow obstruction for 32 years. Interestingly, baseline orthostatic blood pressure decrease, as well as increased resting heart rate, was associated with reduced lung function during follow-up. The authors consequently suggested that subtle signs of cardiovascular autonomic dysfunction may precede the development of chronic obstructive pulmonary disease (COPD).Clinical markers of subtle cardiovascular autonomic dysfunction predict incident COPD: the potential role of neurohumoral activation http://ow.ly/mUcW30jMnPC ER -