TY - JOUR T1 - Differential diagnosis between newly diagnosed asthma and COPD using exhaled breath condensate metabolomics: a pilot study JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.01825-2017 VL - 51 IS - 3 SP - 1701825 AU - Mauro Maniscalco AU - Debora Paris AU - Dominique J. Melck AU - Antonio Molino AU - Mauro Carone AU - Paolo Ruggeri AU - Gaetano Caramori AU - Andrea Motta Y1 - 2018/03/01 UR - http://erj.ersjournals.com/content/51/3/1701825.abstract N2 - Asthma and chronic obstructive pulmonary disease (COPD) are heterogeneous diseases with high pathological burden and healthcare costs [1–3]. In outpatient clinical practice, an accurate differential diagnosis is often very difficult, particularly in adult smokers, requiring specific lung function tests [4, 5]. Since nuclear magnetic resonance (NMR)-based metabolomics of exhaled breath condensate (EBC) discriminates adults with COPD [6–8] or asthma [9] from healthy subjects, we hypothesised that it is also able to differentiate asthma and COPD patients of different severities.NMR profiling of EBC discriminates between asthma and COPD and this may help clinicians with differential diagnosis http://ow.ly/cNGI30hWYAE ER -