TY - JOUR T1 - Sex differences and factors influencing the duration of the QT interval in patients on anti-tuberculosis therapy JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.02368-2017 VL - 51 IS - 2 SP - 1702368 AU - Gerardo Alvarez-Uria AU - Manoranjan Midde Y1 - 2018/02/01 UR - http://erj.ersjournals.com/content/51/2/1702368.abstract N2 - In an ECG, the QT interval represents the depolarisation and repolarisation of the ventricles and is usually corrected for heart rate (QTc). Previous studies have shown that women have a reduced repolarisation reserve and greater susceptibility to the QTc prolongation effect of some drugs [1, 2].Sex has a strong influence on the QTc prolongation effect of first-line TB drugs and gatifloxacin http://ow.ly/UXtP30hJJCuData used in the preparation of this article were obtained from the Platform for Aggregations of Clinical TB Studies (codr.c-path.org). The Platform for Aggregations of Clinical TB Studies initiative is a public–private partnership launched in May 2015 by Critical Path Institute (C-Path), the Special Programme for Research and Training in Tropical Diseases (TDR), the Global Alliance for TB Drug Development (TB Alliance), and St. George's University of London. ER -