RT Journal Article SR Electronic T1 Population-based analysis of COPD patients in Catalonia: implications for case management JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP PA4956 DO 10.1183/1393003.congress-2017.PA4956 VO 50 IS suppl 61 A1 Baltaxe, Erik A1 Roca, Josep A1 Vela, Emili A1 Tenyi, Akos A1 Cano, Isaac A1 Monterde, David A1 Claries, Montse A1 Garcia-Altes, Anna A1 Hernandez, Carme A1 Escarrabill, Joan YR 2017 UL http://erj.ersjournals.com/content/50/suppl_61/PA4956.abstract AB Rationale: Despite substantial progresses on standard of care recommendations, management of Chronic Obstructive Pulmonary (COPD) patients show potential for improvement provided that patients’ heterogeneities are better understood.Objectives: To perform a population-based analysis of the COPD patients in Catalonia (ES) (7,5 M citizens) aiming at exploring the potential of the health registry information to enhance risk assessment and stratification in the clinical arena.Methods: The characteristics of 264,830 COPD cases registered in 2014 in the Health Surveillance System were assessed. Multiple logistic regression analysis was used to elaborate predictive models for four health indicators: (i) mortality, (ii) unplanned hospitalizations (all and COPD-related hospitalizations), (iii) multiple exacerbators, and, (iv) high users of healthcare resources. No clinical, nor forced spirometry data were available.Main Results: Multimorbidity, expressed by GMA (adjusted morbidity groups) scoring, was the covariate with highest impact in the four predictive models. This score explained a substantial percentage of interindividual variability (AUC): (i) mortality (0.763); (ii) unplanned hospitalizations (0.829); (iii) multiple exacerbators (0.766); and, (iv) higher use of healthcare resources (0.803). Patients above the 85 percentile in terms of healthcare costs per year represented 59% of the overall costs of COPD patients.Conclusions: The predictive models stress the explanatory role of the covariate multimorbidity. The results highly encourage further developments fostering interoperability between health registries and electronic health records to enhance clinical risk prediction.