RT Journal Article SR Electronic T1 Pre- and post-lung transplant pulmonary rehabilitation in Hungary JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP PA754 DO 10.1183/1393003.congress-2017.PA754 VO 50 IS suppl 61 A1 János Tamás Varga A1 Krisztina Kelemen A1 Aniko Bohacs A1 Krisztina Czebe A1 George Victor Agathou A1 Maria Kerti A1 Zsuzsanna Balogh A1 Judit Petro A1 Eszter Csiszer A1 Gyorgy Lang YR 2017 UL http://erj.ersjournals.com/content/50/suppl_61/PA754.abstract AB Rationale: The role of pre- and post-lung transplant pulmonary rehabilitation is to maintain and improve exercise capacity, lung mechanics, peripherial- and respiratory muscle function. Aims: Follow-up the changes of functional and quality of life markers in pre- and post-transplant pulmonary rehabilitation. Materials and Methods: 28 patients (16 COPD FEV1:18±6 %pred, 7 IPF TLC: 46±11 %pred, 4 bronchiectasis FEV1: 28±4 %pred, alveolitis fibrotisans TLC: 31 %pred). participated in a pre- and 8 took part in a post-transplant rehabilitation program (primary diagnosis: 5 COPD, 3 IPF). The rehabilitation program consisted of chest wall-stretching, controlled breathing techniques and personalized exercises of 20-30 minutes by cycling and treadmill 2-3 times per day for 4 weeks. Lung function, chest expansion (CE), 6 minutes walking distance (6MWD), modified Medical Research Council Dyspnea Scale (mMRC), COPD Assessment Test (CAT), breath holding time, grip strength were measured.Results: Pre-transplant pulmonary rehabilitation resulted significant improvement in CE (3,06±1,76 vs. 4,40±1,03 cm, p<0,05), CAT (21±6 vs. 16±6), breath holding time (18±9 vs. 30±15 sec), 6MWD (295±99 vs. 332±98m), p<0,05. FEV1, FVC, mMRC, grip strength did not change significantly. Post-transplant rehabilitation resulted significant improvement in CE (3,67±2,76 vs. 5,63±2,06 cm), CAT (17±7 vs. 8±4), breath holding time (26±6 vs. 42±16 sec), FEV1 (53±27 vs. 73±26 %pred) and FVC (56±21 vs. 73±21 %pred), p<0.05. The 6MWD, mMRC and grip strength did not change significantly.Conclusion: Our results underline the importance of perioperative pulmonary rehabilitation in the complex management of lung transplantation.