RT Journal Article
SR Electronic
T1 European Respiratory Society guidelines for the management of adult bronchiectasis
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP 1700629
DO 10.1183/13993003.00629-2017
VO 50
IS 3
A1 Eva Polverino
A1 Pieter C. Goeminne
A1 Melissa J. McDonnell
A1 Stefano Aliberti
A1 Sara E. Marshall
A1 Michael R. Loebinger
A1 Marlene Murris
A1 Rafael Cantón
A1 Antoni Torres
A1 Katerina Dimakou
A1 Anthony De Soyza
A1 Adam T. Hill
A1 Charles S. Haworth
A1 Montserrat Vendrell
A1 Felix C. Ringshausen
A1 Dragan Subotic
A1 Robert Wilson
A1 Jordi Vilaró
A1 Bjorn Stallberg
A1 Tobias Welte
A1 Gernot Rohde
A1 Francesco Blasi
A1 Stuart Elborn
A1 Marta Almagro
A1 Alan Timothy
A1 Thomas Ruddy
A1 Thomy Tonia
A1 David Rigau
A1 James D. Chalmers
YR 2017
UL http://erj.ersjournals.com/content/50/3/1700629.abstract
AB Bronchiectasis in adults is a chronic disorder associated with poor quality of life and frequent exacerbations in many patients. There have been no previous international guidelines.The European Respiratory Society guidelines for the management of adult bronchiectasis describe the appropriate investigation and treatment strategies determined by a systematic review of the literature.A multidisciplinary group representing respiratory medicine, microbiology, physiotherapy, thoracic surgery, primary care, methodology and patients considered the most relevant clinical questions (for both clinicians and patients) related to management of bronchiectasis. Nine key clinical questions were generated and a systematic review was conducted to identify published systematic reviews, randomised clinical trials and observational studies that answered these questions. We used the GRADE approach to define the quality of the evidence and the level of recommendations. The resulting guideline addresses the investigation of underlying causes of bronchiectasis, treatment of exacerbations, pathogen eradication, long term antibiotic treatment, anti-inflammatories, mucoactive drugs, bronchodilators, surgical treatment and respiratory physiotherapy.These recommendations can be used to benchmark quality of care for people with bronchiectasis across Europe and to improve outcomes.The publication of the first ERS guidelines for bronchiectasis http://ow.ly/wQSO30dU0nE