RT Journal Article SR Electronic T1 European Respiratory Society guidelines for the management of adult bronchiectasis JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP 1700629 DO 10.1183/13993003.00629-2017 VO 50 IS 3 A1 Polverino, Eva A1 Goeminne, Pieter C. A1 McDonnell, Melissa J. A1 Aliberti, Stefano A1 Marshall, Sara E. A1 Loebinger, Michael R. A1 Murris, Marlene A1 Cantón, Rafael A1 Torres, Antoni A1 Dimakou, Katerina A1 De Soyza, Anthony A1 Hill, Adam T. A1 Haworth, Charles S. A1 Vendrell, Montserrat A1 Ringshausen, Felix C. A1 Subotic, Dragan A1 Wilson, Robert A1 Vilaró, Jordi A1 Stallberg, Bjorn A1 Welte, Tobias A1 Rohde, Gernot A1 Blasi, Francesco A1 Elborn, Stuart A1 Almagro, Marta A1 Timothy, Alan A1 Ruddy, Thomas A1 Tonia, Thomy A1 Rigau, David A1 Chalmers, James D. YR 2017 UL https://publications.ersnet.org//content/50/3/1700629.abstract AB Bronchiectasis in adults is a chronic disorder associated with poor quality of life and frequent exacerbations in many patients. There have been no previous international guidelines.The European Respiratory Society guidelines for the management of adult bronchiectasis describe the appropriate investigation and treatment strategies determined by a systematic review of the literature.A multidisciplinary group representing respiratory medicine, microbiology, physiotherapy, thoracic surgery, primary care, methodology and patients considered the most relevant clinical questions (for both clinicians and patients) related to management of bronchiectasis. Nine key clinical questions were generated and a systematic review was conducted to identify published systematic reviews, randomised clinical trials and observational studies that answered these questions. We used the GRADE approach to define the quality of the evidence and the level of recommendations. The resulting guideline addresses the investigation of underlying causes of bronchiectasis, treatment of exacerbations, pathogen eradication, long term antibiotic treatment, anti-inflammatories, mucoactive drugs, bronchodilators, surgical treatment and respiratory physiotherapy.These recommendations can be used to benchmark quality of care for people with bronchiectasis across Europe and to improve outcomes.The publication of the first ERS guidelines for bronchiectasis http://ow.ly/wQSO30dU0nE