PT  - JOURNAL ARTICLE
AU  - Eva Polverino
AU  - Pieter C. Goeminne
AU  - Melissa J. McDonnell
AU  - Stefano Aliberti
AU  - Sara E. Marshall
AU  - Michael R. Loebinger
AU  - Marlene Murris
AU  - Rafael Cantón
AU  - Antoni Torres
AU  - Katerina Dimakou
AU  - Anthony De Soyza
AU  - Adam T. Hill
AU  - Charles S. Haworth
AU  - Montserrat Vendrell
AU  - Felix C. Ringshausen
AU  - Dragan Subotic
AU  - Robert Wilson
AU  - Jordi Vilaró
AU  - Bjorn Stallberg
AU  - Tobias Welte
AU  - Gernot Rohde
AU  - Francesco Blasi
AU  - Stuart Elborn
AU  - Marta Almagro
AU  - Alan Timothy
AU  - Thomas Ruddy
AU  - Thomy Tonia
AU  - David Rigau
AU  - James D. Chalmers
TI  - European Respiratory Society guidelines for the management of adult bronchiectasis
AID  - 10.1183/13993003.00629-2017
DP  - 2017 Sep 01
TA  - European Respiratory Journal
PG  - 1700629
VI  - 50
IP  - 3
4099  - http://erj.ersjournals.com/content/50/3/1700629.short
4100  - http://erj.ersjournals.com/content/50/3/1700629.full
SO  - Eur Respir J2017 Sep 01; 50
AB  - Bronchiectasis in adults is a chronic disorder associated with poor quality of life and frequent exacerbations in many patients. There have been no previous international guidelines.The European Respiratory Society guidelines for the management of adult bronchiectasis describe the appropriate investigation and treatment strategies determined by a systematic review of the literature.A multidisciplinary group representing respiratory medicine, microbiology, physiotherapy, thoracic surgery, primary care, methodology and patients considered the most relevant clinical questions (for both clinicians and patients) related to management of bronchiectasis. Nine key clinical questions were generated and a systematic review was conducted to identify published systematic reviews, randomised clinical trials and observational studies that answered these questions. We used the GRADE approach to define the quality of the evidence and the level of recommendations. The resulting guideline addresses the investigation of underlying causes of bronchiectasis, treatment of exacerbations, pathogen eradication, long term antibiotic treatment, anti-inflammatories, mucoactive drugs, bronchodilators, surgical treatment and respiratory physiotherapy.These recommendations can be used to benchmark quality of care for people with bronchiectasis across Europe and to improve outcomes.The publication of the first ERS guidelines for bronchiectasis http://ow.ly/wQSO30dU0nE