PT  - JOURNAL ARTICLE
AU  - Rochwerg, Bram
AU  - Brochard, Laurent
AU  - Elliott, Mark W.
AU  - Hess, Dean
AU  - Hill, Nicholas S.
AU  - Nava, Stefano
AU  - Navalesi, Paolo
AU  - Antonelli, Massimo
AU  - Brozek, Jan
AU  - Conti, Giorgio
AU  - Ferrer, Miquel
AU  - Guntupalli, Kalpalatha
AU  - Jaber, Samir
AU  - Keenan, Sean
AU  - Mancebo, Jordi
AU  - Mehta, Sangeeta
AU  - Raoof, Suhail
TI  - Official ERS/ATS clinical practice guidelines: noninvasive ventilation for acute respiratory failure
AID  - 10.1183/13993003.02426-2016
DP  - 2017 Aug 01
TA  - European Respiratory Journal
PG  - 1602426
VI  - 50
IP  - 2
4099  - http://erj.ersjournals.com/content/50/2/1602426.short
4100  - http://erj.ersjournals.com/content/50/2/1602426.full
SO  - Eur Respir J2017 Aug 01; 50
AB  - Noninvasive mechanical ventilation (NIV) is widely used in the acute care setting for acute respiratory failure (ARF) across a variety of aetiologies. This document provides European Respiratory Society/American Thoracic Society recommendations for the clinical application of NIV based on the most current literature.The guideline committee was composed of clinicians, methodologists and experts in the field of NIV. The committee developed recommendations based on the GRADE (Grading, Recommendation, Assessment, Development and Evaluation) methodology for each actionable question. The GRADE Evidence to Decision framework in the guideline development tool was used to generate recommendations. A number of topics were addressed using technical summaries without recommendations and these are discussed in the supplementary material.This guideline committee developed recommendations for 11 actionable questions in a PICO (population–intervention–comparison–outcome) format, all addressing the use of NIV for various aetiologies of ARF. The specific conditions where recommendations were made include exacerbation of chronic obstructive pulmonary disease, cardiogenic pulmonary oedema, de novo hypoxaemic respiratory failure, immunocompromised patients, chest trauma, palliation, post-operative care, weaning and post-extubation.This document summarises the current state of knowledge regarding the role of NIV in ARF. Evidence-based recommendations provide guidance to relevant stakeholders.ERS/ATS evidence-based recommendations for the use of noninvasive ventilation in acute respiratory failure http://ow.ly/NrqB30dAYSQ